ArticlePlant molecular biology2007
The serine-rich N-terminal region of Arabidopsis phytochrome A is required for protein stability.
Article in Plant molecular biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Assessing the Role of PPKs in Phosphorylating Phytochrome A Using the Protoplast Transient Expression System.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Liquid-liquid phase separation of TZP promotes PPK-mediated phosphorylation of the phytochrome A photoreceptor.Nature plants · 2024Article
- Two Distinct Molecular Types of Phytochrome A in Plants: Evidence of Existence and Implications for Functioning.International journal of molecular sciences · 2023Review
- Phytochrome A in plants comprises two structurally and functionally distinct populations - water-soluble phyA' and amphiphilic phyA″.Biophysical reviews · 2022Review
- A LexA-based yeast two-hybrid system for studying light-switchable interactions of phytochromes with their interacting partners.aBIOTECH · 2021Article
- Carotenoid Biosynthesis and Plastid Development in Plants: The Role of Light.International journal of molecular sciences · 2021Review
- Molecular mechanisms underlying phytochrome-controlled morphogenesis in plants.Nature communications · 2019Review
- Genome-wide analysis reveals the evolution and structural features of WRINKLED1 in plants.Molecular genetics and genomics : MGG · 2019Article
- Inheritance and Quantitative Trait Locus Mapping ofFrontiers in plant science · 2019Article
- TANDEM ZINC-FINGER/PLUS3 Is a Key Component of Phytochrome A Signaling.The Plant cell · 2018Article
- Article
- From photon to signal in phytochromes: similarities and differences between prokaryotic and plant phytochromes.Journal of plant research · 2016Review
- Lysine 206 in Arabidopsis phytochrome A is the major site for ubiquitin-dependent protein degradation.Journal of biochemistry · 2016Article
- Degradation of the ABA co-receptor ABI1 by PUB12/13 U-box E3 ligases.Nature communications · 2015Article
- The phytochrome B/phytochrome C heterodimer is necessary for phytochrome C-mediated responses in rice seedlings.PloS one · 2014Article
- Conditional involvement of constitutive photomorphogenic1 in the degradation of phytochrome A.Plant physiology · 2013Article
- Phosphorylation of phytochrome B inhibits light-induced signaling via accelerated dark reversion in Arabidopsis.The Plant cell · 2013Article
- Effects of missense mutation on structure and function of photoreceptor.Plant signaling & behavior · 2012Article
- Missense mutation in the amino terminus of phytochrome A disrupts the nuclear import of the photoreceptor.Plant physiology · 2012Article
- Phytochrome A-specific signaling in Arabidopsis thaliana.Plant signaling & behavior · 2011Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deletion or substitution of the serine-rich N-terminal stretch of grass phytochrome A (phyA) has repeatedly been shown to yield a hyperactive photoreceptor when expressed under the control of a constitutive promoter in transgenic tobacco or Arabidopsis seedlings retaining their native phyA. These observations have lead to the proposal that the serine-rich region is involved in negative regulation of phyA signaling. To re-evaluate this conclusion in a more physiological context we produced transgenic Arabidopsis seedlings of the phyA-null background expressing Arabidopsis PHYA deleted in the sequence corresponding to amino acids 6-12, under the control of the native PHYA promoter. Compared to the transgenic seedlings expressing wild-type phyA, the seedlings bearing the mutated phyA showed normal responses to pulses of far-red (FR) light and impaired responses to continuous FR light. In yeast two-hybrid experiments, deleted phyA interacted normally with FHY1 and FHL, which are required for phyA accumulation in the nucleus. Immunoblot analysis showed reduced stability of deleted phyA under continuous red or FR light. The reduced physiological activity can therefore be accounted for by the enhanced destruction of the mutated phyA. These findings do not support the involvement of the serine-rich region in negative regulation but they are consistent with a recent report suggesting that phyA turnover is regulated by phosphorylation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.