ReviewJournal of gastroenterology2006
Recent insights into digestive motility in functional dyspepsia.
Review in Journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- [Clinical practice guideline on the management of patients with dyspepsia. Update 2012].Atencion primaria · 2012Guideline
- Trial
- Can mosapride citrate reduce the volume of lavage solution for colonoscopy preparation?World journal of gastroenterology · 2013Trial
- Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation.World journal of gastroenterology · 2012Trial
- Effect of domperidone therapy on nocturnal dyspeptic symptoms of functional dyspepsia patients.World journal of gastroenterology · 2010Trial
- Associations of Functional Dyspepsia with Eating Behaviors and Stress-Coping Styles Among Japanese University Students.Nutrients · 2026Article
- Effect of stomach motility on food hydrolysis and gastric emptying: Insight from computational models.Physics of fluids (Woodbury, N.Y. : 1994) · 2022Article
- Impacts of heat stress on meat quality and strategies for amelioration: a review.International journal of biometeorology · 2020Review
- Electroacupuncture for Functional Constipation: A Multicenter, Randomized, Control Trial.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract.PloS one · 2017Article
- Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling for the Inhibition of Acetylcholinesterase by Acotiamide, A Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, in Rat Stomach.Pharmaceutical research · 2016Article
- Association of anxiety, depression, and psychological distress in people with and without functional dyspepsia.Advanced biomedical research · 2016Article
- The Pharmacological Effects of Benachio-F(®) on Rat Gastrointestinal Functions.Biomolecules & therapeutics · 2015Article
- Pimpinella anisum in the treatment of functional dyspepsia: A double-blind, randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Tibetan herbal formula Padma Digestin modulates gastrointestinal motility in vitro.World journal of gastrointestinal pharmacology and therapeutics · 2013Article
- Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism.World journal of gastroenterology · 2012Article
- Simotang enhances gastrointestinal motility, motilin and cholecystokinin expression in chronically stressed mice.World journal of gastroenterology · 2011Article
- The 5-HT4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage.Journal of gastroenterology · 2010Article
- Mosapride in gastrointestinal disorders.Drugs · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional gastrointestinal disorders, such as functional dyspepsia (FD) and irritable bowel syndrome, are common pathologies of the gut. FD is a clinical syndrome defined as chronic or recurrent pain or discomfort of unknown origin in the upper abdomen. The pathophysiological mechanisms responsible for FD have not been fully elucidated, but new ideas regarding its pathophysiology and the significance of the pathophysiology with respect to the symptom pattern of FD have emerged. In particular, there is growing interest in alterations in gastric motility, such as accommodation to a meal or gastric emptying, and visceral sensation in FD. The mechanisms underlying impaired gastroduodenal motor function are unclear, but possible factors include abnormal neurohormonal function, autonomic dysfunction, visceral hypersensitivity to acid or mechanical distention, Helicobacter pylori infection, acute gastrointestinal infection, psychosocial comorbidity, and stress. Although the optimum treatment for FD is not yet clearly established, acid-suppressive drugs, prokinetic agents, eradication of H. pylori, and antidepressants have been widely used in the management of patients with FD. The therapeutic efficacy of prokinetics such as itopride hydrochloride and mosapride citrate in the treatment of FD is supported by the results of relatively large and well-controlled studies. In addition, recent research has yielded new therapeutic agents and modalities for dysmotility in FD, including agonists/antagonists of various sensorimotor receptors, activation of the nitrergic pathway, kampo medicine, acupuncture, and gastric electric stimulation. This review discusses recent research on the pathophysiology of and treatment options for FD, with special attention given to digestive dysmotility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.