ArticleNature biotechnology2006
Antibacterial discovery and development--the failure of success?
Article in Nature biotechnology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed.
- Minimal Computational Framework for Systematic Identification of Antimicrobial Targets.bioRxiv : the preprint server for biology · 2026Article
- Genomic insights and biosynthetic gene cluster analysis ofMicrobiology spectrum · 2026Article
- Repurposed bunamidine disrupts envelope energetics and induces ROS-mediated non-lytic killing.AMB Express · 2026Article
- Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function.BMC research notes · 2025Article
- SAMP: Identifying antimicrobial peptides by an ensemble learning model based on proportionalized split amino acid composition.Briefings in functional genomics · 2024Article
- SAMP: Identifying Antimicrobial Peptides by an Ensemble Learning Model Based on Proportionalized Split Amino Acid Composition.bioRxiv : the preprint server for biology · 2024Article
- Article
- Impact of Beta-Lactam Target Attainment on Resistance Development in Patients with Gram-Negative Infections.Antibiotics (Basel, Switzerland) · 2023Article
- Laser Treatment Increases the Antimicrobial Efficacy of Cyanobacterial Extracts againstInternational journal of environmental research and public health · 2022Article
- Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome.Molecules (Basel, Switzerland) · 2022Article
- Inhibition of Filamentous Thermosensitive Mutant-Z Protein inMolecules (Basel, Switzerland) · 2022Article
- Article
- Antimicrobial Resistance in the COVID-19 Landscape: Is There an Opportunity for Anti-Infective Antibodies and Antimicrobial Peptides?Frontiers in immunology · 2022Review
- Controlling the pyridinium-zwitterionic ligand ratio on atomically precise gold nanoclusters allowing for eradicating Gram-positive drug-resistant bacteria and retaining biocompatibility.Chemical science · 2021Article
- Nutritional and Functional Properties of Colostrum in Puppies and Kittens.Animals : an open access journal from MDPI · 2021Review
- Critical appraisal of the mechanisms of gastrointestinal and hepatobiliary infection by COVID-19.American journal of physiology. Gastrointestinal and liver physiology · 2021Article
- Facilitating Compound Entry as a Means to Discover Antibiotics for Gram-Negative Bacteria.Accounts of chemical research · 2021Review
- Development of an Antibiotic Resistance Breaker to Resensitize Drug-ResistantFrontiers in cellular and infection microbiology · 2021Article
- Exploring Nurses' Perception of Antibiotic Use and Resistance: A Qualitative Inquiry.Journal of multidisciplinary healthcare · 2021Article
- Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A combination of approaches and compounds-many of which failed to yield immediate results in the past-will ultimately prove invaluable to the drug industry in the ongoing battle against infectious disease.
Indexed as
Identifiers
17160049What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.