Evidence map›Paper›PMID 17157572›Full record

ReviewBone2007

Metabolic consideration of epiphyseal growth: survival responses in a taxing environment.

Irving M Shapiro, Vickram Srinivas

Open access · greenAbstract readReview
In one paragraph

Review in Bone, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. The hypertrophic chondrocyte: To be or not to be.Histology and histopathology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Irving M ShapiroDepartment of Orthopaedic Surgery, Thomas Jefferson University Philadelphia, Philadelphia, PA 19107, USA. irving.shapiro@jefferson.edu
Vickram Srinivas
Thomas Jefferson University · US

Funding

Regeneration of Nucleus Pulposus by Tissue EngineeringR01AR050087 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI RISBUD, MAKARAND V, SHAPIRO, IRVING M · 2005 to 2013
$3.0M
BONE GROWTH IN DENTAL, CRANIAL AND SKELETAL TISSUESR01DE010875 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI SHAPIRO, IRVING M · 1994 to 2006
$2.4M
Oxygen Sensing and Growth Plate Chrondrocyte MaturationR01DE016383 · NIDCR · THOMAS JEFFERSON UNIVERSITY · PI SRINIVAS, VICKRAM · 2005 to 2009
$1.4M
CRANIOFACIAL DEVELOPMENT: METABOLIC CONTROL OF APOPTOSISR01DE013319 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI SHAPIRO, IRVING M · 1999 to 2003
$1.1M
HIF Prolyl Hydroxylases and Chondrocyte MaturationR03DE015694 · NIDCR · THOMAS JEFFERSON UNIVERSITY · PI SRINIVAS, VICKRAM · 2004 to 2005
$157k
REGULATION OF APOPTOSIS IN OSTEOBLAST-LIKE CELLSF32DE005748 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI ADAMS, CHRISTOPHER S · 2001 to 2003
$148k
NIAMS NIH HHS AR050087NIAMS NIH HHS R01 AR050087NIDCR NIH HHS DE05748NIDCR NIH HHS DE13319NIDCR NIH HHS DE15694NIDCR NIH HHS DE16383NIDCR NIH HHS F32 DE005748NIDCR NIH HHS R01 DE010875NIDCR NIH HHS R01 DE013319NIDCR NIH HHS R01 DE016383NIDCR NIH HHS R03 DE015694
6 · The paper itself

Abstract

The goal of this review is to examine some of the metabolic features of the maturing chondrocyte within the epiphyseal growth plate. The energy status of the tissue is examined in light of the energy needs of the tissue and the availability of oxygen. The role of HIF, PHDs and other proteins concerned with transduction of the oxemic response is considered and related to chondrocyte survival in a complex extracellular matrix.

Indexed as

AnimalsCell SurvivalChondrocytesGrowth PlateHumansOxygenOxygen

Identifiers

PMID17157572
PMCPMC1941712
OpenAlexW2046656076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.