Evidence map›Paper›PMID 1715684›Full record

ArticleThe Biochemical journal1991

Association of the HNK-1 epitope with 5'-nucleotidase from Torpedo marmorata (electric ray) electric organ.

M Vogel, H J Kowalewski, H Zimmermann, A Janetzko, R U Margolis, H E Wollny

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

M VogelAK Neurochemie, Zoologisches Institut der J.W. Goethe-Universität, Frankfurt am Main, Federal Republic of Germany.
H J Kowalewski
H Zimmermann
A Janetzko
R U Margolis
H E Wollny
Goethe University Frankfurt · DEColumbia University Irving Medical Center · USDarmstadt University of Applied Sciences · DE

Funding

NEURONAL CELL-SURFACE GLYCOCONJUGATESR01NS026283 · NINDS · NEW YORK UNIVERSITY · PI MARGOLIS, RICHARD U · 1989 to 1991
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NINDS NIH HHS NS-26283
6 · The paper itself

Abstract

5'-Nucleotidase isolated from the electric organ of the electric ray (Torpedo marmorata) has a molecular mass of 62 kDa and, on two-dimensional electrophoresis, separates into up to 13 isoforms within a pI range of 5.9-6.7. The N-terminal sequence data show a 71% identity over 17 amino acids with that previously published for the rat liver enzyme. All forms of 5'-nucleotidase are recognized by the HNK-1 monoclonal antibody. HNK-1 immunoreactivity is found at the surface of the Schwann-cell processes covering the synaptic terminals and in this respect corresponds to that of 5'-nucleotidase in the same tissue. Since a number of glycoproteins involved in cell recognition and cell adhesion carry the HNK-1 epitope, 5'-nucleotidase may play a role in cell-cell or cell-extracellular matrix interaction in addition to its activity as an enzyme.

Indexed as

Torpedo5'-NucleotidaseAmino Acid SequenceAnimalsAntibodies, MonoclonalAntigens, DifferentiationBlotting, WesternCD57 AntigensElectric OrganImmunoenzyme TechniquesIsoelectric PointMicroscopy, ElectronMolecular Sequence DataMolecular Weight5'-NucleotidaseAntibodies, MonoclonalAntigens, DifferentiationCD57 Antigens

Identifiers

PMID1715684
PMCPMC1151468
OpenAlexW2337221096

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.