Evidence map›Paper›PMID 17156809›Full record

ArticleVirology2007

Full-length sequence analysis of SIVmus in wild populations of mustached monkeys (Cercopithecus cephus) from Cameroon provides evidence for two co-circulating SIVmus lineages.

Avelin F Aghokeng, Elizabeth Bailes, Severin Loul, Valerie Courgnaud, Eitel Mpoudi-Ngolle, Paul M Sharp, Eric Delaporte, Martine Peeters

Open access · greenAbstract read
In one paragraph

Article in Virology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  2. CD4 receptor diversity in chimpanzees protects against SIV infection.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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  15. Origins of HIV and the AIDS pandemic.Cold Spring Harbor perspectives in medicine · 2011
    Review
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  19. Extensive survey on the prevalence and genetic diversity of SIVs in primate bushmeat provides insights into risks for potential new cross-species transmissions.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2010
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Avelin F AghokengLaboratoire Retrovirus, UMR 145, IRD and the Department of International Health, University of Montpellier I, Montpellier, France.
Elizabeth Bailes
Severin Loul
Valerie Courgnaud
Eitel Mpoudi-Ngolle
Paul M Sharp
Eric Delaporte
Martine Peeters
Université de Montpellier · FRUniversity of Nottingham · GB

Funding

Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1M
NIAID NIH HHS R01 AI050529NIAID NIH HHS R01 AI 50529
6 · The paper itself

Abstract

Mustached monkeys (Cercopithecus cephus), which form a significant component of primate bushmeat in west central Africa, are infected with simian immunodeficiency virus (SIVmus). We identified and genetically characterized five new SIVmus strains infecting wild living mustached monkeys from Cameroon. Phylogenetic analysis of partial pol sequences revealed that SIVmus strains form two distinct groups within the clade comprised of lentiviruses isolated from Cercopithecus nictitans (SIVgsn), Cercopithecus mona (SIVmon) and C. cephus (SIVmus). Characterisation of three full-length SIVmus genomes confirmed the presence of two distinct lineages infecting mustached monkeys. These two variants of SIVmus, here designated SIVmus-1 and SIVmus-2, were isolated from animals sharing habitats within the same geographic region. Phylogenetic analyses showed that the diversification of SIVmus, SIVgsn and SIVmon involved inter-lineage recombination, and suggested that one of the SIVmus lineages likely resulted from cross-species transmission and recombination involving SIVmus and an as yet uncharacterized SIV. These results indicate that cross-species transmission and recombination play a major role in the evolution of primate lentiviruses among sympatric primate species.

Indexed as

Genome, ViralAnimalsBase SequenceCameroonCercopithecusEvolution, MolecularGenes, polMolecular Sequence DataPhylogenyRNA, ViralSequence Analysis, DNASequence Homology, Nucleic AcidSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusRNA, Viral

Identifiers

PMID17156809
PMCPMC1900428
OpenAlexW2126271805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.