ArticleEpidemiology and infection2007
Burden of community-onset bloodstream infection: a population-based assessment.
Article in Epidemiology and infection, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00870623 (Procalcitonin and Endotoxin Sequential Levels to Optimize the Treatment of Bloodstream Infections), which is not on this map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Procalcitonin and Endotoxin Sequential Levels to Optimize the Treatment of Bloodstream Infections
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- MALDI-TOF mass spectrometry rapid pathogen identification and outcomes of patients with bloodstream infection: A systematic review and meta-analysis.Microbial biotechnology · 2022Pooled it
- A systematic review of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry compared to routine microbiological methods for the time taken to identify microbial organisms from positive blood cultures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Pooled it
- In-depth analysis of T2Bacteria positive results in patients with concurrent negative blood culture: a case series.BMC infectious diseases · 2020Trial
- Developing Machine-Learning Models to Predict Bacteremia in Febrile Adults Presenting to the Emergency Department: A Retrospective Cohort Study from a Large Center.The western journal of emergency medicine · 2025Article
- Observational
- Red blood cell distribution width to albumin ratio as a predictor of mortality in ICU patients with community acquired bacteremia.Scientific reports · 2024Observational
- Polymicrobial bloodstream infections per se do not increase mortality compared to monomicrobial bloodstream infections in sepsis patients: a Korean nationwide sepsis cohort study.BMC infectious diseases · 2024Article
- Mandatory surveillance of bacteremia conducted by automated monitoring.Frontiers in public health · 2024Article
- Using an Antibiogram Profile to Improve Infection Control and Rational Antimicrobial Therapy in an Urban Hospital in The Gambia, Strategies and Lessons for Low- and Middle-Income Countries.Antibiotics (Basel, Switzerland) · 2023Article
- Usefulness of procalcitonin at admission as a risk-stratifying biomarker for 50-day in-hospital mortality among patients with community-acquired bloodstream infection: an observational cohort study.Biomarker research · 2023Article
- Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury.Northern clinics of Istanbul · 2023Article
- Impact of phenotypic rapid diagnostic assay on duration of empiric antibiotics for gram-negative bacteremia.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Predicting Bacteremia among Septic Patients Based on ED Information by Machine Learning Methods: A Comparative Study.Diagnostics (Basel, Switzerland) · 2022Article
- Risk Factors and Outcomes of Bloodstream Infections Among People With Human Immunodeficiency Virus: A Longitudinal Cohort Study From 2000 to 2017.Open forum infectious diseases · 2022Article
- Review
- Prevalence and Mortality Associated with Bloodstream Organisms: a Population-Wide Retrospective Cohort Study.Journal of clinical microbiology · 2022Article
- Microorganism Distributions and Antimicrobial Susceptibility in Community-Onset Bacteremia: A 6-Year Longitudinal Multicenter Cohort in Southern Taiwan.Journal of acute medicine · 2022Article
- Identification of Prognostic Factors in Patients With Streptococcus Bloodstream Infection.Frontiers in medicine · 2022Article
- Real-World Evaluation of the Impact of Implementation of the Virtuo Blood Culture System in a Tertiary Care Hospital.Journal of clinical microbiology · 2021Article
- Comparative clinical characteristics and outcomes of patients with community acquired bacteremia caused by Escherichia coli, Burkholderia pseudomallei and Staphylococcus aureus: A prospective observational study (Ubon-sepsis).PLoS neglected tropical diseases · 2021Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although community-onset bloodstream infection (BSI) is recognized to be a major cause of morbidity and mortality, there is a paucity of population-based studies defining its overall burden. We conducted population-based laboratory surveillance for all community-onset BSI in the Calgary Health Region during 2000-2004. A total of 4467 episodes of community-onset BSI were identified for an overall annual incidence of 81.6/100,000. The three species, Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae were responsible for the majority of community-onset BSI; they occurred at annual rates of 25.8, 13.5, and 10.1/100,000, respectively. Overall 3445/4467 (77%) episodes resulted in hospital admission representing 0.7% of all admissions to major acute care hospitals. The subsequent hospital length of stay was a median of 9 (interquartile range, 5-15) days; the total days of acute hospitalization attributable to community-onset BSI was 51,146 days or 934 days/100,000 annually. Four hundred and sixty patients died in hospital for a case-fatality rate of 13%. Community-onset BSI is common and has a major patient and societal impact. These data support further efforts to reduce the burden of community-onset BSI.
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Registered trials
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