ArticlePediatric nephrology (Berlin, Germany)2007
Renal scarring sequelae in childhood Kawasaki disease.
Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Article
- Clinical features of acute kidney injury in patients with Kawasaki disease.World journal of clinical pediatrics · 2018Review
- Response to "Acute kidney injury occurs only rarely in patients with Kawasaki disease".Pediatric research · 2017Article
- An atypical case of a 2-year-old boy with acute kidney injury: a race against time. Answers.Pediatric nephrology (Berlin, Germany) · 2017Article
- Urinary Lactate Dehydrogenase Activity and Its Isozyme Patterns in Kawasaki Disease.International journal of pediatrics · 2017Article
- Acute kidney injury in patients with Kawasaki disease.Pediatric research · 2016Article
- Pyuria in patients with Kawasaki disease.World journal of clinical pediatrics · 2015Review
- Natriuretic Peptides in Kawasaki Disease: the Myocardial Perspective.Diagnostics (Basel, Switzerland) · 2013Review
- Kidney and urinary tract involvement in kawasaki disease.International journal of pediatrics · 2013Review
- Clinical characteristics of Kawasaki disease with sterile pyuria.Korean journal of pediatrics · 2013Article
- Nephrotic syndrome in Kawasaki disease: a report of three cases.Pediatric nephrology (Berlin, Germany) · 2012Article
- Pyuria associated with acute Kawasaki disease and fever from other causes.The Pediatric infectious disease journal · 2009Article
- Sterile pyuria in patients with Kawasaki disease originates from both the urethra and the kidney.Pediatric nephrology (Berlin, Germany) · 2007Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess renal inflammation and its sequelae in Kawasaki disease (KD) patients, we conducted a prospective study in a university medical center setting in Taiwan. From June 2002 to January 2005, 50 children with KD were enrolled, and after admission, all received technetium-99m dimercaptosuccinic acid scintigraphy single photon emission computed tomography (DMSA renal SPECT), the results of which were used as the reference standard for determining renal inflammation. Patients with renal inflammation underwent another DMSA renal SPECT more than 6 months later to evaluate the sequelae. We found that 26 of the 50 patients (52%) had renal inflammatory foci. There were no significant relationships between clinical or laboratory parameters and renal involvement in KD, except the presence of coronary artery lesions [P<0.01; odds ratio (OR) 5.18; 95% confidence interval (CI) 1.52-17.65]. Although all patients were free of clinical symptoms, the 6-month follow-up DMSA renal SPECT showed renal scarring in 11 of the 24 patients (46%). Patients with an initial abnormal renal ultrasound did predict a greatly increased risk of scarring (P<0.05; OR 16.2; 95% CI 1.27-206.20). In conclusion, this study demonstrated that the potential long-term clinical impact of KD is not limited to coronary artery lesion sequelae but also includes renal scar formation.
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