ArticleGenetics2007
Mitochondrial genome sequence evolution in Chlamydomonas.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Article
- Efficient enhancement of the antimicrobial activity of Chlamydomonas reinhardtii extract by transgene expression and molecular modification using ionizing radiation.Biotechnology for biofuels and bioproducts · 2024Article
- Long-Read-Based Hybrid Genome Assembly and Annotation of Snow Algal Strain CCCryo 101-99 (cf. Sphaerocystis sp., Chlamydomonadales).Genome biology and evolution · 2024Article
- Article
- Article
- Article
- Relative Mutation Rates in Nucleomorph-Bearing Algae.Genome biology and evolution · 2019Article
- Multiple Independent Changes in Mitochondrial Genome Conformation in Chlamydomonadalean Algae.Genome biology and evolution · 2017Article
- Selenocystamine improves protein accumulation in chloroplasts of eukaryotic green algae.AMB Express · 2015Article
- Mutation rates in plastid genomes: they are lower than you might think.Genome biology and evolution · 2015Article
- Photosynthetic biomanufacturing in green algae; production of recombinant proteins for industrial, nutritional, and medical uses.Photosynthesis research · 2015Review
- Article
- The mitochondrial genome sequence of the ciliate Paramecium caudatum reveals a shift in nucleotide composition and codon usage within the genus Paramecium.BMC genomics · 2011Article
- Micro-algae come of age as a platform for recombinant protein production.Biotechnology letters · 2010Review
- Evolution of linear mitochondrial DNA in three known lineages of Polytomella.Current genetics · 2010Article
- The Dunaliella salina organelle genomes: large sequences, inflated with intronic and intergenic DNA.BMC plant biology · 2010Article
- Nucleotide diversity of the Chlamydomonas reinhardtii plastid genome: addressing the mutational-hazard hypothesis.BMC evolutionary biology · 2009Article
- The mitochondrial and plastid genomes of Volvox carteri: bloated molecules rich in repetitive DNA.BMC genomics · 2009Article
- Nucleotide diversity in the mitochondrial and nuclear compartments of Chlamydomonas reinhardtii: investigating the origins of genome architecture.BMC evolutionary biology · 2008Article
- The microalga Chlamydomonas reinhardtii as a platform for the production of human protein therapeutics.Bioengineered bugsArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mitochondrial genomes of the Chlorophyta exhibit significant diversity with respect to gene content and genome compactness; however, quantitative data on the rates of nucleotide substitution in mitochondrial DNA, which might help explain the origin of this diversity, are lacking. To gain insight into the evolutionary forces responsible for mitochondrial genome diversification, we sequenced to near completion the mitochondrial genome of the chlorophyte Chlamydomonas incerta, estimated the evolutionary divergence between Chlamydomonas reinhardtii and C. incerta mitochondrial protein-coding genes and rRNA-coding regions, and compared the relative evolutionary rates in mitochondrial and nuclear genes. Synonymous and nonsynonymous substitution rates do not differ significantly between the mitochondrial and nuclear protein-coding genes. The mitochondrial rRNA-coding regions, however, are evolving much faster than their nuclear counterparts, and this difference might be explained by relaxed functional constraints on the mitochondrial translational apparatus due to the small number of proteins synthesized in Chlamydomonas mitochondria. Substitution rates at synonymous sites in a nonstandard mitochondrial gene (rtl) and at intronic and synonymous sites in nuclear genes expressed at low levels suggest that the mutation rate is similar in these two genetic compartments. Potential evolutionary forces shaping mitochondrial genome evolution in Chlamydomonas are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.