Evidence map›Paper›PMID 17151068›Full record

ArticleNucleic acids research2007

The Rat Genome Database, update 2007--easing the path from disease to data and back again.

Simon N Twigger, Mary Shimoyama, Susan Bromberg, Anne E Kwitek, Howard J Jacob, RGD Team

Abstract read
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. GABAIUPHAR/BPS guide to pharmacology CITE · 2021
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. GABAergic neurogliaform cells represent local sources of insulin in the cerebral cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  8. Article
  9. Article
  10. Article
  11. Genetic basis of the impaired renal myogenic response in FHH rats.American journal of physiology. Renal physiology · 2013
    Article
  12. Obesity gene atlas in mammals.Journal of genomics · 2013
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simon N TwiggerDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. simont@mcw.edu
Mary Shimoyama
Susan Bromberg
Anne E Kwitek
Howard J Jacob
RGD Team

Funding

RAT GENOME DATABASER01HL064541 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ANNE E. KWITEK · 1999 to 2026
$50.0M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Gene Ontology ConsortiumP41HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2004 to 2011
$27.4M
GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
NHGRI NIH HHS HG-002273NHGRI NIH HHS P41 HG002273NHGRI NIH HHS R01 HG002273NHGRI NIH HHS U41 HG002273NHLBI NIH HHS HL-64541NHLBI NIH HHS R01 HL064541
6 · The paper itself

Abstract

The Rat Genome Database (RGD, http://rgd.mcw.edu) is one of the core resources for rat genomics and recent developments have focused on providing support for disease-based research using the rat model. Recognizing the importance of the rat as a disease model we have employed targeted curation strategies to curate genes, QTL and strain data for neurological and cardiovascular disease areas. This work has centered on rat but also includes data for mouse and human to create 'disease portals' that provide a unified view of the genes, QTL and strain models for these diseases across the three species. The disease curation efforts combined with normal curation activities have served to greatly increase the content of the database, particularly for biological information, including gene ontology, disease, pathway and phenotype ontology annotations. In addition to improving the features and database content, community outreach has been expanded to demonstrate how investigators can leverage the resources at RGD to facilitate their research and to elicit suggestions and needs for future developments. We have published a number of papers that provide additional information on the ontology annotations and the tools at RGD for data mining and analysis to better enable researchers to fully utilize the database.

Indexed as

Databases, GeneticDisease Models, AnimalGenomicsAnimalsCardiovascular DiseasesChromosome MappingHumansInternetMiceNervous System DiseasesQuantitative Trait LociRatsUser-Computer Interface

Identifiers

PMID17151068
PMCPMC1761441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.