ArticleMethods of information in medicine2006
The Common Data Elements for cancer research: remarks on functions and structure.
Article in Methods of information in medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- A community-engaged approach to developing common data elements: a case study from the RADx-UP Long COVID common data elements Task Force.JAMIA open · 2025Article
- Toward Better Semantic Interoperability of Data Element Repositories in Medicine: Analysis Study.JMIR medical informatics · 2024Article
- Common Data Elements Reported in Mechanical Thrombectomy for Acute Ischemic Stroke: A Systematic Review of Active Clinical Trials.Brain sciences · 2022Review
- Domain-Specific Common Data Elements for Rare Disease Registration: Conceptual Approach of a European Joint Initiative Toward Semantic Interoperability in Rare Disease Research.JMIR medical informatics · 2022Article
- Consensus core clinical data elements for meningiomas (v2021.1).Neuro-oncology · 2022Article
- Pragmatic MDR: a metadata repository with bottom-up standardization of medical metadata through reuse.BMC medical informatics and decision making · 2021Article
- The landscape of nutri-informatics: a review of current resources and challenges for integrative nutrition research.Database : the journal of biological databases and curation · 2021Review
- Modeling cancer clinical trials using HL7 FHIR to support downstream applications: A case study with colorectal cancer data.International journal of medical informatics · 2021Article
- Composite CDE: modeling composite relationships between common data elements for representing complex clinical data.BMC medical informatics and decision making · 2020Article
- Clinical MetaData ontology: a simple classification scheme for data elements of clinical data based on semantics.BMC medical informatics and decision making · 2019Article
- The 2019 mathematical oncology roadmap.Physical biology · 2019Review
- QLBMC medical informatics and decision making · 2019Article
- Cervical cancer screening research in the PROSPR I consortium: Rationale, methods and baseline findings from a US cohort.International journal of cancer · 2019Article
- Big data management challenges in health research-a literature review.Briefings in bioinformatics · 2019Review
- Unleashing the value of Common Data Elements through the CEDAR Workbench.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2019Article
- Recommendations for Improving the Quality of Rare Disease Registries.International journal of environmental research and public health · 2018Article
- A Collaborative, Network-Based Approach to Advance Women's Depression Research in the United States: Preliminary Findings.Journal of women's health (2002) · 2018Article
- Common data elements for secondary use of electronic health record data for clinical trial execution and serious adverse event reporting.BMC medical research methodology · 2016Article
- An exploratory study using an openEHR 2-level modeling approach to represent common data elements.Journal of the American Medical Informatics Association : JAMIA · 2016Article
- Using Semantic Web technologies for the generation of domain-specific templates to support clinical study metadata standards.Journal of biomedical semantics · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectivesThe National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent the elements necessary to support its intended purpose, and whether it could prevent errors and inconsistencies from being accidentally introduced. We also performed automated checks for certain types of content errors that provided a rough measure of curation quality.
methodsEvaluation was performed on CDE content downloaded via the NCI's CDE Browser, and transformed into relational database form. Evaluation was performed under three categories: 1) compatibility with the ISO/IEC 11179 metadata model, on which CDE structure is based, 2) features necessary for controlled vocabulary support, and 3) support for a stated NCI goal, set up of data collection forms for cancer research.
resultsVarious limitations were identified both with respect to content (inconsistency, insufficient definition of elements, redundancy) as well as structure--particularly the need for term and relationship support, as well as the need for metadata supporting the explicit representation of electronic forms that utilize sets of common data elements.
conclusionsWhile there are numerous positive aspects to the CDE effort, there is considerable opportunity for improvement. Our recommendations include review of existing content by diverse experts in the cancer community; integration with the NCI thesaurus to take advantage of the latter's links to nationally used controlled vocabularies, and various schema enhancements required for electronic form support.
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17149500PMC2980785What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.