ArticleBiology letters2005
Genetic influences on variation in female orgasmic function: a twin study.
Article in Biology letters, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 128 citations in OpenAlex.
- Sexual self-care, quality of sexual life and fertility desire in women attending comprehensive health centers in Urmia, Iran.BMC women's health · 2025Article
- Hominid sexual nature.Theory in biosciences = Theorie in den Biowissenschaften · 2020Article
- Sexuality after Male-to-Female Gender Affirmation Surgery.BioMed research international · 2018Article
- Determinants of female sexual orgasms.Socioaffective neuroscience & psychology · 2016Article
- The existing therapeutic interventions for orgasmic disorders: recommendations for culturally competent services, narrative review.Iranian journal of reproductive medicine · 2015Article
- Cohort Profile: TwinsUK and healthy ageing twin study.International journal of epidemiology · 2013Article
- Sexual activity and impairment in women with systemic sclerosis compared to women from a general population sample.PloS one · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Orgasmic dysfunction in females is commonly reported in the general population with little consensus on its aetiology. We performed a classical twin study to explore whether there were observable genetic influences on female orgasmic dysfunction. Adult females from the TwinsUK register were sent a confidential survey including questions on sexual problems. Complete responses to the questions on orgasmic dysfunction were obtained from 4037 women consisting of 683 monozygotic and 714 dizygotic pairs of female twins aged between 19 and 83 years. One in three women (32%) reported never or infrequently achieving orgasm during intercourse, with a corresponding figure of 21% during masturbation. A significant genetic influence was seen with an estimated heritability for difficulty reaching orgasm during intercourse of 34% (95% confidence interval 27-40%) and 45% (95% confidence interval 38-52%) for orgasm during masturbation. These results show that the wide variation in orgasmic dysfunction in females has a genetic basis and cannot be attributed solely to cultural influences. These results should stimulate further research into the biological and perhaps evolutionary processes governing female sexual function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.