Intensive insulin therapy in intensive care: an example of the struggle to implement evidence-based medicine.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset.Critical care (London, England) · 2008
   Pooled it
2. Implementing glucose control in intensive care: a multicenter trial using statistical process control.Intensive care medicine · 2010
   Trial
3. Treating hyperglycemia and diabetes with insulin therapy: transition from inpatient to outpatient care.Medscape journal of medicine · 2008
   Trial
4. Comparison of multiple machine learning methods for predicting postoperative hyperglycemia in patients without diabetes undergoing cardiac surgery.Frontiers in cardiovascular medicine · 2025
   Article
5. "One more thing to think about…" Cognitive burden experienced by intensive care unit nurses when implementing a tight glucose control protocol.Journal of diabetes science and technology · 2012
   Review
6. Insulin therapy in critically ill patients.Vascular health and risk management · 2010
   Review
7. Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trials.Critical care (London, England) · 2010
   Review
8. The impact of early hypoglycemia and blood glucose variability on outcome in critical illness.Critical care (London, England) · 2009
   Article
9. Why are clinicians not embracing the results from pivotal clinical trials in severe sepsis? A bayesian analysis.PloS one · 2008
   Article
10. The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered.Intensive care medicine · 2008
    Article
11. Nurse-led implementation of an insulin-infusion protocol in a general intensive care unit: improved glycaemic control with increased costs and risk of hypoglycaemia signals need for algorithm revision.BMC nursing · 2008
    Article
12. Is there more to glycaemic control than meets the eye?Critical care (London, England) · 2007
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

5 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as