ArticleInfection and immunity2007
Protective effect of the Nramp1 BB genotype against Brucella abortus in the water buffalo (Bubalus bubalis).
Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- A previously uncharacterized Fur-family metalloregulator integrates iron- and manganese-sensing to control virulence gene regulatory networks in Brucella.Scientific reports · 2025Article
- TLR2 c.374C>T variant linked to natural resistance against brucellosis in Italian Mediterranean river buffalo.BMC veterinary research · 2025Article
- Association Analysis ofAnimals : an open access journal from MDPI · 2025Article
- Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025Review
- The Goat Cytotoxic T Lymphocyte-Associated Antigen-4 Gene: mRNA Expression and Association Analysis of Insertion/Deletion Variants with the Risk of Brucellosis.International journal of molecular sciences · 2024Article
- Genetic epidemiology of the Alpine ibex reservoir of persistent and virulent brucellosis outbreak.Scientific reports · 2020Article
- Evaluation of the association of SLC11A1 gene polymorphism with incidence of paratuberculosis in goats.Journal of genetics · 2017Article
- Case-control approach application for finding a relationship between candidate genes and clinical mastitis in Holstein dairy cattle.Journal of applied genetics · 2016Article
- Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease.PloS one · 2015Article
- In-vitro indicators of natural resistance and milk-producing ability in dairy buffaloes (Bubalus bubalis).Journal of applied animal welfare science : JAAWS · 2015Article
- Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis).BMC genetics · 2014Article
- Polymorphism of cytokine and innate immunity genes associated with bovine brucellosis in cattle.Molecular biology reports · 2014Article
- Detection of antibodies against Brucella abortus, Leptospira spp., and Apicomplexa protozoa in water buffaloes in the Northeast of Argentina.Tropical animal health and production · 2013Article
- Genetic analysis of the 3' untranslated region of the bovine SLC11A1 gene reveals novel polymorphisms.Molecular biology reports · 2013Article
- Effect of polymorphisms in the Slc11a1 coding region on resistance to brucellosis by macrophages in vitro and after challenge in two Bos breeds (Blanco Orejinegro and Zebu).Genetics and molecular biology · 2010Article
- The manganese transporter MntH is a critical virulence determinant for Brucella abortus 2308 in experimentally infected mice.Infection and immunity · 2009Article
- Mannose-binding lectin haplotypes influence Brucella abortus infection in the water buffalo (Bubalus bubalis).Immunogenetics · 2008Article
- NRAMP1 3' untranslated region polymorphisms are not associated with natural resistance to Brucella abortus in cattle.Infection and immunity · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We tested 413 water buffalo cows (142 cases and 271 controls) for the presence of anti-Brucella abortus antibodies (by the skin test, the agglutination test, and the complement fixation test) and the Nramp1 genotype (by capillary electrophoresis). Four alleles (Nramp1A, -B, -C, and -D) were detected in the 3' untranslated region of the Nramp1 gene. The BB genotype was represented among only controls, providing evidence that this genotype confers resistance to Brucella abortus. The monocytes from the BB (resistant) subjects displayed a higher basal level of Nramp1 mRNA and a lower number of viable intracellular bacteria than did the monocytes from AA (susceptible) subjects. The higher basal level of the antibacterial protein Nramp1 most probably provides the BB animals with the possibility of controlling bacteria immediately after their entry inside the cell.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.