ArticleJournal of medical ethics2006
A public health perspective on research ethics.
Article in Journal of medical ethics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- When communities are really in control: ethical issues surrounding community mobilisation for dengue prevention in Mexico and Nicaragua.BMC public health · 2017Trial
- Ethical challenges in cluster randomized controlled trials: experiences from public health interventions in Africa and Asia.Bulletin of the World Health Organization · 2009Trial
- The Increasing Influence of Big Tech in Health and Medicine and the Need for a Public Health Ethics Perspective.Public health ethics · 2025Article
- Pharmacovigilance and bioethics: the importance of a neglected relationship.Frontiers in drug safety and regulation · 2025Review
- Reimagining research ethics to include environmental sustainability: a principled approach, including a case study of data-driven health research.Journal of medical ethics · 2023Article
- Changes in Health-Related Quality of Life During Rehabilitation in Patients With Operable Lung Cancer: A Feasibility Study (PROLUCA).Integrative cancer therapies · 2018Article
- The Ebola clinical trials: a precedent for research ethics in disasters.Journal of medical ethics · 2018Article
- Practical and Ethical Aspects of Advance Research Directives for Research on Healthy Aging: German and Israeli Professionals' Perspectives.Frontiers in medicine · 2018Article
- Implementing a Public Health Objective for Alcohol Premises Licensing in Scotland: A Qualitative Study of Strategies, Values, and Perceptions of Evidence.International journal of environmental research and public health · 2017Article
- Perioperative Rehabilitation in Operable Lung Cancer Patients (PROLUCA): A Feasibility Study.Integrative cancer therapies · 2016Article
- FDA's Proposed Guidance for Laboratory Developed Tests: How Should Regulators Balance the Risks and Promise of Innovation in Clinical Genetics?FDLI's food and drug policy forum · 2015Article
- Deception in research is morally problematic … and so too is not using it morally: reply to open peer commentaries on "the use of deception in public health behavioral intervention trials: a case study of three online alcohol trials".The American journal of bioethics : AJOB · 2014Article
- The use of deception in public health behavioral intervention trials: a case study of three online alcohol trials.The American journal of bioethics : AJOB · 2013Article
- Risk-benefit analysis: from a logical point of view.Journal of bioethical inquiry · 2012Article
- Informed recruitment in partner studies of HIV transmission: an ethical issue in couples research.BMC medical ethics · 2009Article
- Is "rescue" therapy ethical in randomized controlled trials?Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2009Review
- Autonomy, paternalism, and justice: ethical priorities in public health.American journal of public health · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethical guidelines for conducting clinical trials have historically been based on a perceived therapeutic obligation to treat and benefit the patient-participants. The origins of this ethical framework can be traced to the Hippocratic oath originally written to guide doctors in caring for their patients, where the overriding moral obligation of doctors is strictly to do what is best for the individual patient, irrespective of other social considerations. In contrast, although medicine focuses on the health of the person, public health is concerned with the health of the entire population, and thus, public health ethics is founded on the societal responsibility to protect and promote the health of the population as a whole. From a public health perspective, research ethics should be guided by giving due consideration to the risks and benefits to society in addition to the individual research participants. On the basis of a duty to protect the population as a whole, a fiduciary obligation to realise the social value of the research and the moral responsibility to distribute the benefits and burdens of research fairly across society, how a public health perspective on research ethics results in fundamental re-assessments of the proper course of action for two salient topical issues in research ethics is shown: stopping trials early for reasons of efficacy and the conduct of research on less expensive yet less effective interventions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.