Evidence map›Paper›PMID 17145239›Full record

SynthesisThe American journal of medicine2006

Valerian for sleep: a systematic review and meta-analysis.

Stephen Bent, Amy Padula, Dan Moore, Michael Patterson, Wolf Mehling

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The American journal of medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  5. Clinical guideline for the evaluation and management of chronic insomnia in adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2008
    Guideline
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephen BentOsher Center for Integrative Medicine, University of California, San Francisco, CA 94121, USA. stephen.bent@ucsf.edu
Amy Padula
Dan Moore
Michael Patterson
Wolf Mehling

Funding

Early Identification of Adverse Reactions to HerbsK08AT001338 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BENT, STEPHEN W · 2003 to 2007
$608k
NCCIH NIH HHS K08 AT001338PHS HHS 1 K08 ATO1338-01
6 · The paper itself

Abstract

Insomnia affects approximately one-third of the adult population and contributes to increased rates of absenteeism, health care use, and social disability. Extracts of the roots of valerian (Valeriana officinalis) are widely used for inducing sleep and improving sleep quality. A systematic review of randomized, placebo-controlled trials of valerian for improving sleep quality is presented. An extensive literature search identified 16 eligible studies examining a total of 1093 patients. Most studies had significant methodologic problems, and the valerian doses, preparations, and length of treatment varied considerably. A dichotomous outcome of sleep quality (improved or not) was reported by 6 studies and showed a statistically significant benefit (relative risk of improved sleep = 1.8, 95% confidence interval, 1.2-2.9), but there was evidence of publication bias in this summary measure. The available evidence suggests that valerian might improve sleep quality without producing side effects. Future studies should assess a range of doses of standardized preparations of valerian and include standard measures of sleep quality and safety.

Indexed as

PhytotherapyPlant RootsValerianHumansPlant ExtractsSleep Initiation and Maintenance DisordersPlant Extracts

Identifiers

PMID17145239
PMCPMC4394901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.