ReviewStem cell reviews2005
The contribution of epidermal stem cells to skin cancer.
Review in Stem cell reviews, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The remarkable legacy of the K6/ODC mouse: mechanisms of polyamine-promoted tumorigenesis revealed.Amino acids · 2026Review
- Long-term Effects of 222-nm ultraviolet radiation C Sterilizing Lamps on Mice Susceptible to Ultraviolet Radiation.Photochemistry and photobiology · 2020Article
- Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells.Molecules and cells · 2018Review
- Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines.Cancer growth and metastasis · 2015Review
- Emerging understanding of multiscale tumor heterogeneity.Frontiers in oncology · 2014Review
- A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.Molecular carcinogenesis · 2013Article
- Epidermal stem cells and their epigenetic regulation.International journal of molecular sciences · 2013Review
- Biochemistry of epidermal stem cells.Biochimica et biophysica acta · 2013Review
- Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic.Toxicological sciences : an official journal of the Society of Toxicology · 2012Article
- Induction of human squamous cell-type carcinomas by arsenic.Journal of skin cancer · 2011Article
- Are stem cell niches shared for skin cancers?Pigment cell & melanoma research · 2010Article
- Article
- Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics.Cancer research · 2008Article
- Keratinocyte stem cells and the targets for nonmelanoma skin cancer.Photochemistry and photobiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Tumors arising from the skin are of multiple phenotypes, with differing degrees of malignant potential. In mouse models of skin carcinogenesis, tumors of squamous phenotype are the most common; however, human disease indicates that multiple phenotypes may arise from a common pool of stem cells that are then influenced by epigenetic factors. The use of transgenic and knockout gene technologies with mice is unraveling some of the specific genes regulating fate determination in stem cells other than squamous lineage, including basal cell carcinoma and sebaceous adenomas. The following review examines the evidence for the stem cell origin of epidermal tumors and the contribution of some specific gene families toward stem cell fate decisions during epidermal tumor progression.
Indexed as
Identifiers
17142859What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.