ReviewJournal of mammary gland biology and neoplasia2006
Analysis of lactation defects in transgenic mice.
Review in Journal of mammary gland biology and neoplasia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogseLife · 2023Article
- Got Milk? Identifying and Characterizing Lactation Defects in Genetically-Engineered Mouse Models.Journal of mammary gland biology and neoplasia · 2020Review
- Scribble promotes alveologenesis in the pregnant mammary gland for milk production.Reproduction (Cambridge, England) · 2020Article
- Attenuation of Mammary Gland Dysplasia and Feeding Difficulties in Tabby Mice by Fetal Therapy.Journal of mammary gland biology and neoplasia · 2018Article
- Milk lipid regulation at the maternal-offspring interface.Seminars in cell & developmental biology · 2018Review
- ATM is required for SOD2 expression and homeostasis within the mammary gland.Breast cancer research and treatment · 2017Article
- Survival and growth of C57BL/6J mice lacking the BK channel,Physiological reports · 2017Article
- Unexpected severe consequences of Pikfyve deletion by aP2- or Aq-promoter-driven Cre expression for glucose homeostasis and mammary gland development.Physiological reports · 2016Article
- Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland.Oncogene · 2015Article
- Essential role of Orai1 store-operated calcium channels in lactation.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.The Journal of biological chemistry · 2014Article
- Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation.PloS one · 2014Article
- Comparative transcriptome analyses reveal conserved and distinct mechanisms in ovine and bovine lactation.Functional & integrative genomics · 2013Article
- A post-GWAS replication study confirming the PTK2 gene associated with milk production traits in Chinese Holstein.PloS one · 2013Article
- Milk ejection in mice LG/J x SM/J.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Article
- Monotremes and marsupials: comparative models to better understand the function of milk.Journal of biosciences · 2012Article
- SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling.Development (Cambridge, England) · 2012Article
- Smooth muscle α actin is specifically required for the maintenance of lactation.Developmental biology · 2012Article
- Evaluation of mammary gland development and function in mouse models.Journal of visualized experiments : JoVE · 2011Article
- Maternal absence of the parathyroid hormone 2 receptor affects postnatal pup development.Journal of neuroendocrinology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Although lactation is the only physiological function of the mammary gland, little is known about the molecular events required for secretory activation and milk production. Genetically altered mice have been used extensively to study mammary gland development during puberty and pregnancy, as well as mammary tumorigenesis. A number of approaches have been used to produce genetic modifications in mammary glands of mice, including transgenic mice utilizing mammary specific promoters, traditional knockout mice, mammary-specific gene deletion, and conditionally-regulated transgenes. The same technologies can be used to study secretory activation and lactation; however only a comparatively small number of studies to date have used these approaches to study these events. In this paper we review the technologies available to make genetically modified mice for the study of secretory activation and lactation as well as specific analytical procedures that can be used to characterize mice with lactation defects.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.