ArticleJournal of clinical microbiology2007
Using a resequencing microarray as a multiple respiratory pathogen detection assay.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 136 citations in OpenAlex.
- Antibody Phage Display Technology for Sensor-Based Virus Detection: Current Status and Future Prospects.Biosensors · 2023Review
- A full genome tiling array enhanced the inspection and quarantine of SARS-CoV-2.Virology journal · 2023Article
- Article
- Acoustical Slot Mode Sensor for the Rapid Coronaviruses Detection.Sensors (Basel, Switzerland) · 2021Article
- A resequencing pathogen microarray method for high-throughput molecular diagnosis of multiple etiologies associated with central nervous system infection.Archives of virology · 2017Article
- DNA Microarray Detection of 18 Important Human Blood Protozoan Species.PLoS neglected tropical diseases · 2016Article
- Application of Multiplex PCR Coupled with Matrix-Assisted Laser Desorption Ionization-Time of Flight Analysis for Simultaneous Detection of 21 Common Respiratory Viruses.Journal of clinical microbiology · 2015Article
- Solid and Suspension Microarrays for Microbial Diagnostics.Methods in microbiology · 2015Article
- Association of targeted multiplex PCR with resequencing microarray for the detection of multiple respiratory pathogens.Frontiers in microbiology · 2015Article
- DNA microarray for detection of gastrointestinal viruses.Journal of clinical microbiology · 2015Article
- Review
- Visual analysis of DNA microarray data for accurate molecular identification of non-albicans Candida isolates from patients with candidemia episodes.Journal of clinical microbiology · 2013Article
- Evolving gene targets and technology in influenza detection.Molecular diagnosis & therapy · 2013Review
- Viral surveillance and discovery.Current opinion in virology · 2013Review
- Article
- Leapfrog diagnostics: Demonstration of a broad spectrum pathogen identification platform in a resource-limited setting.Health research policy and systems · 2012Article
- Use and evaluation of molecular diagnostics for pneumonia etiology studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012Review
- Development of a flow-through [corrected] microarray based reverse transcriptase multiplex ligation-dependent probe amplification assay for the detection of European Bunyaviruses. [corrected].Molecular biotechnology · 2011Article
- Application of a broad-range resequencing array for detection of pathogens in desert dust samples from Kuwait and Iraq.Applied and environmental microbiology · 2011Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simultaneous testing for detection of infectious pathogens that cause similar symptoms (e.g., acute respiratory infections) is invaluable for patient treatment, outbreak prevention, and efficient use of antibiotic and antiviral agents. In addition, such testing may provide information regarding possible coinfections or induced secondary infections, such as virally induced bacterial infections. Furthermore, in many cases, detection of a pathogen requires more than genus/species-level resolution, since harmful agents (e.g., avian influenza virus) are grouped with other, relatively benign common agents, and for every pathogen, finer resolution is useful to allow tracking of the location and nature of mutations leading to strain variations. In this study, a previously developed resequencing microarray that has been demonstrated to have these capabilities was further developed to provide individual detection sensitivity ranging from 10(1) to 10(3) genomic copies for more than 26 respiratory pathogens while still retaining the ability to detect and differentiate between close genetic neighbors. In addition, the study demonstrated that this system allows unambiguous and reproducible sequence-based strain identification of the mixed pathogens. Successful proof-of-concept experiments using clinical specimens show that this approach is potentially very useful for both diagnostics and epidemic surveillance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.