ArticleNucleic acids research2007
SNP@Ethnos: a database of ethnically variant single-nucleotide polymorphisms.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Functional and genetic predisposition to rhinovirus lower respiratory tract infections in prematurely born infants.European journal of pediatrics · 2016Article
- Article
- Genetic predisposition of RSV infection-related respiratory morbidity in preterm infants.European journal of pediatrics · 2014Article
- Identification of ethnically specific genetic variations in pan-asian ethnos.Genomics & informatics · 2014Article
- dbPSHP: a database of recent positive selection across human populations.Nucleic acids research · 2014Article
- Safety paradigm: genetic evaluation of therapeutic grade human embryonic stem cells.Journal of the Royal Society, Interface · 2010Review
- Shrunken methodology to genome-wide SNPs selection and construction of SNPs networks.BMC systems biology · 2010Article
- Article
- Stable patterns of gene expression regulating carbohydrate metabolism determined by geographic ancestry.PloS one · 2009Article
- Single-nucleotide polymorphism bioinformatics: a comprehensive review of resources.Circulation. Cardiovascular genetics · 2009Review
- SNP@Evolution: a hierarchical database of positive selection on the human genome.BMC evolutionary biology · 2009Article
- A survey of the population genetic variation in the human kinome.Journal of human genetics · 2009Article
- LCT 13910 C/T polymorphism, serum calcium, and bone mineral density in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009Article
- Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.American journal of human genetics · 2008Article
- Effective selection of informative SNPs and classification on the HapMap genotype data.BMC bioinformatics · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inherited genetic variation plays a critical but largely uncharacterized role in human differentiation. The completion of the International HapMap Project makes it possible to identify loci that may cause human differentiation. We have devised an approach to find such ethnically variant single-nucleotide polymorphisms (ESNPs) from the genotype profile of the populations included in the International HapMap database. We selected ESNPs using the nearest shrunken centroid method (NSCM), and performed multiple tests for genetic heterogeneity and frequency spectrum on genes having ESNPs. The function and disease association of the selected SNPs were also annotated. This resulted in the identification of 100 736 SNPs that appeared uniquely in each ethnic group. Of these SNPs, 1009 were within disease-associated genes, and 85 were predicted as damaging using the Sorting Intolerant From Tolerant system. This study resulted in the creation of the SNP@Ethnos database, which is designed to make this type of detailed genetic variation approach available to a wider range of researchers. SNP@Ethnos is a public database of ESNPs with annotation information that currently contains 100 736 ESNPs from 10 138 genes, and can be accessed at http://variome.net and http://bioportal.net/ or directly at http://bioportal.kobic.re.kr/SNPatETHNIC/.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.