ReviewJournal of applied genetics2006
Unintended consequences of plant transformation: a molecular insight.
Review in Journal of applied genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 143 citations in OpenAlex.
- Non-targeted metabolite profiling reveals substantial equivalence of omega-3 enrichedGM crops & food · 2026Article
- Green synthesis revolution: harnessing biological factories for sustainable insect pheromone production in agriculture.Frontiers in plant science · 2026Review
- Impact of Domestication on Floral Traits and Rewards: A Comparison Between Wild and Domesticated Squash (Ecology and evolution · 2025Article
- StMYB308L and its regulatory role in flavonoid biosynthesis pathways in potato.BMC plant biology · 2025Article
- Arabidopsis as a model for translational research.The Plant cell · 2025Review
- Systematic investigation and validation of peanut genetic transformation via the pollen tube injection method.Plant methods · 2024Article
- A Fast, Efficient, and Tissue-Culture-Independent Genetic Transformation Method forPlants (Basel, Switzerland) · 2024Article
- A simple and efficient in planta transformation method based on the active regeneration capacity of plants.Plant communications · 2024Article
- Effect of T-DNA Integration on Growth of TransgenicInternational journal of molecular sciences · 2023Article
- Stable and reproducible expression of bacterialFrontiers in plant science · 2022Article
- Transcriptomic Analysis of Mature Transgenic Poplar Expressing the Transcription FactorFrontiers in bioengineering and biotechnology · 2022Article
- Obtaining Salt Stress-Tolerant Eggplant Somaclonal Variants from In Vitro Selection.Plants (Basel, Switzerland) · 2021Article
- Datura genome reveals duplications of psychoactive alkaloid biosynthetic genes and high mutation rate following tissue culture.BMC genomics · 2021Article
- Article
- Expression of Bt Protein in Transgenic Bt Cotton Plants and Ecological Fitness of These Plants in Different Habitats.Frontiers in plant science · 2020Article
- Problem Formulation for Off-Target Effects of Externally Applied Double-Stranded RNA-Based Products for Pest Control.Frontiers in plant science · 2020Article
- Comprehensive transcriptomics and proteomics analyses ofJournal of biosciences · 2019Article
- The Rooting of Stem Cuttings and the Stability ofPlants (Basel, Switzerland) · 2019Article
- The evolving EU regulatory framework for precision breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs).Frontiers in bioengineering and biotechnology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant genomes are dynamic structures having both the system to maintain and accurately reproduce the information encoded therein and the ability to accept more or less random changes, which is one of the foundations of evolution. Crop improvement and various uncontrolled stress factors can induce unintended genetic and epigenetic variations. In this review it is attempted to summarize factors causing such changes and the molecular nature of these variations in transgenic plants. Unintended effects in transgenic plants can be divided into three main groups: first, pleiotropic effects of integrated DNA on the host plant genome; second, the influence of the integration site and transgene architecture on transgene expression level and stability; and third, the effect of various stresses related to tissue handling, regeneration and clonal propagation. Many of these factors are recently being redefined due to new researches, which apply modern highly sensitive analytical techniques and sequenced model organisms. The ability to inspect large portions of genomes clearly shows that tissue culture contributes to a vast majority of observed genetic and epigenetic changes. Nevertheless, monitoring of thousands transcripts, proteins and metabolites reveals that unintended variation most often falls in the range of natural differences between landraces or varieties. We expect that an increasing amount of evidence on many important crop species will support these observations in the nearest future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.