Evidence map›Paper›PMID 17132878›Full record

ReviewStem cell reviews2005

Plasticity of epidermal stem cells: survival in various environments.

Jackie R Bickenbach, Matthew M Stern

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Biochemistry of epidermal stem cells.Biochimica et biophysica acta · 2013
    Review
  2. The effect of porcine ADM to improve the burn wound healing.International journal of clinical and experimental pathology · 2013
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jackie R BickenbachDepartment of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA. jackie-bickenbach@uiowa.edu
Matthew M Stern
University of Iowa · US

Funding

Age-related Responses of Epidermal Stem Cells to EnvironR01AG020913 · NIA · UNIVERSITY OF IOWA · PI BICKENBACH, JACKIE R · 2002 to 2006
$1.1M
Epidermal Stem Cells Can Reverse Their Fate in Developm*R21AR048398 · NIAMS · UNIVERSITY OF IOWA · PI BICKENBACH, JACKIE R · 2001 to 2002
$147k
SELECTION AND CHARACTERIZATION OF EPIDERMAL STEM CELLSR01AR045259 · NIAMS · UNIVERSITY OF IOWA · PI BICKENBACH, JACKIE R · 1997 to 1999
–
NIAMS NIH HHS R01-AR45259NIAMS NIH HHS R21-AR48398NIA NIH HHS R01-AG20913
6 · The paper itself

Abstract

The keratinocyte cell compartment in the continuously renewing epidermis of the skin is maintained by undifferentiated, self-renewing stem cells. We show that a small subpopulation of epidermal stem cells (EpiSCs) have the capacity to integrate into multiple tissues. These EpiSCs can change their phenotype in direct response of changes in cytokines in vitro, changes in cocultured cells, after injection into damaged environments in vivo. These changes appear to be unrelated to the age of the EpiSC. Even though we can isolate these cells and show that the age of thses cells appears to be irrelevant to this multipotent function, we still do not know how such cells are defined within a tissue or what the life span of a multipotent stem cell is.

Indexed as

Epidermal CellsAnimalsBone Marrow CellsCell DifferentiationCell SurvivalEpidermisHumansMiceModels, AnimalStem CellsStem Cell TransplantationStromal Cells

Identifiers

PMID17132878
OpenAlexW2326241249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.