ReviewAdvances in clinical chemistry2006
Pathogenic mechanisms of anti-endothelial cell antibodies (AECA): their prevalence and clinical relevance.
Review in Advances in clinical chemistry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Serum epitope-specific anti-recoverin autoantibodies as biomarkers for lupus retinopathy.Arthritis research & therapy · 2026Article
- Serological distribution of anti-endothelial cell antibodies and their association with laboratory indicators in autoimmune and immune-mediated diseases.Clinical rheumatology · 2025Article
- Disturbed Complement Receptor Expression Pattern of B Cells Is Enhanced by Toll-like Receptor CD180 Ligation in Diffuse Cutaneous Systemic Sclerosis.International journal of molecular sciences · 2024Article
- Circulating Anti-Endothelial Cell Antibodies in Patients with Geographic Atrophy Related to Dry Age-Related Macular Degeneration.Medicina (Kaunas, Lithuania) · 2024Article
- Neuropsychiatric Systemic Lupus Erythematosus: Molecules Involved in Its Imunopathogenesis, Clinical Features, and Treatment.Molecules (Basel, Switzerland) · 2024Review
- [Anti-endothelial cell antibodies in predicting early miscarriage].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Article
- Anti-Endothelial Cell Antibodies are not frequently elevated in hospitalized patients with COVID-19.Acta bio-medica : Atenei Parmensis · 2022Article
- The impact of anti-endothelial cell antibodies (AECAs) on the development of blood vessel damage in patients with systemic lupus erythematosus: the preliminary study.Rheumatology international · 2022Article
- Anti-Endothelial Cell Antibodies are not frequently elevated in hospitalized patients with COVID-19.Acta bio-medica : Atenei Parmensis · 2022Article
- Article
- Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease.Clinical and experimental immunology · 2013Article
- Article
- Anti-endothelial cell antibodies in rheumatic heart disease.Clinical and experimental immunology · 2010Article
- Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE.Nature reviews. Rheumatology · 2009Review
- Autoantibodies in primary sclerosing cholangitis.World journal of gastroenterology · 2008Review
- Agonistic anti-ICAM-1 antibodies in scleroderma: activation of endothelial pro-inflammatory cascades.Vascular pharmacologyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anti-endothelial cell antibodies (AECA) represent a heterogeneous family of autoantibodies directed against structural endothelial proteins, as well as antigens adhering to endothelial cells. Although AECA immunoassays still show a high-interlaboratory variability, several findings suggest a pathogenic role of these autoantibodies in diseases characterized by endothelial damage. In this chapter, we analyze the knowledge about AECA prevalence, clinical relevance, and their pathogenic role in autoimmune diseases focusing in particular on systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis (SSc), and systemic vasculitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.