Evidence map›Paper›PMID 17129723›Full record

ArticleBiosensors & bioelectronics2007

Profiling of molecular interactions in real time using acoustic detection.

Benjamin Godber, Mark Frogley, Marian Rehak, Alexander Sleptsov, Kevin S J Thompson, Yildiz Uludag, Matthew A Cooper

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 21 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin GodberAkubio Ltd., Unit 181 Cambridge Science Park, Cambridge CB4 0GJ, UK.
Mark Frogley
Marian Rehak
Alexander Sleptsov
Kevin S J Thompson
Yildiz Uludag
Matthew A Cooper

Funding

Acoustic detection of viruses bacteria and toxinsU01AI061243 · NIAID · CAMBRIDGE MEDICAL INNOVATIONS LTD · PI COOPER, MATTHEW A · 2005 to 2008
$2.9M
NIAID NIH HHS U01 AI061243
6 · The paper itself

Abstract

Acoustic sensors that exploit resonating quartz crystals to directly detect the binding of an analyte to a receptor are finding increasing utility in the quantification of clinically relevant analytes. We have developed a novel acoustic detection technology, which we term resonant acoustic profiling (RAP). This technology builds on the fundamental basics of the "quartz crystal microbalance" or "QCM" with several key additional features including two- or four-channel automated sample delivery, in-line referencing and microfluidic sensor 'cassettes' that are pre-coated with easy-to-use surface chemistries. Example applications are described for the quantification of myoglobin concentration and its interaction kinetics, and for the ranking of enzyme-cofactor specificities.

Indexed as

Biosensing TechniquesMicrofluidicsKineticsProtein BindingProteinsProteins

Identifiers

PMID17129723
PMCPMC1994559
OpenAlexW2008819491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.