ArticleGenomics, proteomics & bioinformatics2006
Glia maturation factor gamma (GMFG): a cytokine-responsive protein during hematopoietic lineage development and its functional genomics analysis.
Article in Genomics, proteomics & bioinformatics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Molecular characterization ofOpen veterinary journal · 2026Article
- LncCE: Landscape of Cellularly-elevated lncRNAs in Single Cells Across Normal and Cancer Tissues.Genomics, proteomics & bioinformatics · 2025Article
- Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages.Journal of leukocyte biology · 2024Article
- G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.Aging and disease · 2024Article
- Article
- Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells.Stem cell research & therapy · 2023Article
- Article
- GMFG Has Potential to Be a Novel Prognostic Marker and Related to Immune Infiltrates in Breast Cancer.Frontiers in oncology · 2021Article
- Patient-derived xenografts of central nervous system metastasis reveal expansion of aggressive minor clones.Neuro-oncology · 2020Article
- Canine Bone Marrow-derived Mesenchymal Stem Cells: Genomics, Proteomics and Functional Analyses of Paracrine Factors.Molecular & cellular proteomics : MCP · 2019Article
- Glia maturation factor-γ regulates murine macrophage iron metabolism and M2 polarization through mitochondrial ROS.Blood advances · 2019Article
- GMF as an Actin Network Remodeling Factor.Trends in cell biology · 2018Review
- Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.The Journal of biological chemistry · 2016Article
- Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls.Human molecular genetics · 2013Article
- Glia maturation factor-γ mediates neutrophil chemotaxis.Journal of leukocyte biology · 2011Article
- Identification of CD13+CD36+ cells as a common progenitor for erythroid and myeloid lineages in human bone marrow.Experimental hematology · 2007Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Human hematopoiesis was evaluated using the techniques of controlled stem cell differentiation, two-dimensional gel electrophoresis-based proteomics, and functional genomics. We provide the first report that glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. Results from global functional genomics analysis indicate that GMFG possesses several other features: hematopoietic tissue-specific gene expression, a promoter concentrated with high-score hematopoiesis-specific transcription factors, and possible molecular coevolution with a rudimentary blood/immune system. On the basis of our findings, we hypothesize that GMFG is a hematopoietic-specific protein that may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.