ReviewChromosoma2007
The right dose for every sex.
Review in Chromosoma, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 50 citations in OpenAlex.
- Cell-Type Specific Variation in X-Chromosome Dosage Compensation in Drosophila.microPublication biology · 2025Article
- Interaction of Male Specific Lethal complex and genomic imbalance on global gene expression in Drosophila.Scientific reports · 2021Article
- Correct dosage of X chromosome transcription is controlled by a nuclear pore component.Cell reports · 2021Article
- Regulation of p53 by E3s.Cancers · 2021Review
- Histone modifications in the male germ line of Drosophila.BMC developmental biology · 2013Article
- Article
- Article
- Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1.Nature structural & molecular biology · 2011Article
- Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.Chromosoma · 2010Article
- The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine.Biochimica et biophysica acta · 2010Review
- Imprinting of the Y chromosome influences dosage compensation in roX1 roX2 Drosophila melanogaster.Genetics · 2009Article
- Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1.PLoS genetics · 2009Article
- Buffering of segmental and chromosomal aneuploidies in Drosophila melanogaster.PLoS genetics · 2009Article
- Two classes of dosage compensation complex binding elements along Caenorhabditis elegans X chromosomes.Molecular and cellular biology · 2009Article
- Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis.BMC genomics · 2009Article
- MSL2 promotes Mdm2-independent cytoplasmic localization of p53.The Journal of biological chemistry · 2009Article
- X chromosomal regulation in flies: when less is more.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2009Article
- Cold-induced alteration in the global structure of the male sex chromosome of In1BM2(reinverted) of Drosophila melanogaster is associated with increased acetylation of histone 4 at lysine 16.Journal of genetics · 2008Article
- SU(VAR)3-7 links heterochromatin and dosage compensation in Drosophila.PLoS genetics · 2008Article
- Transcription-coupled methylation of histone H3 at lysine 36 regulates dosage compensation by enhancing recruitment of the MSL complex in Drosophila melanogaster.Molecular and cellular biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex chromosomes in different organisms are studied as model systems for chromatin regulation of transcription and epigenetics. Similar to the female X in mammals, the male X chromosome in Drosophila is involved in the process of dosage compensation. However, in contrast to one of the mammalian female X chromosomes undergoing inactivation, the Drosophila male X is transcriptionally upregulated by approximately twofold. The Drosophila male X is a remarkable example for a specialized, transcriptionally hyperactive chromatin domain that facilitates the study of chromatin regulation in the context of transcription, nuclear architecture, and chromatin remodeling. In addition, the rich phenomenology of dosage compensation in Drosophila provides an opportunity to explore the complexities of gene regulation through epigenetic chromatin configurations, histone modifications, and noncoding RNAs. Male-specific lethal (MSL) factors constitute the MSL complex or dosage compensation complex and are important for transcription regulation of X-linked genes. Recent biochemical studies have identified a number of interesting factors that associate with the MSL complex including components of the nuclear pore complex and exosome subunits. Furthermore, global analysis of MSL complex binding showed that MSL complexes are enriched on genes with preferential binding to 3' end of genes. Taken together, these findings suggest a role of the MSL complex in transcription elongation, RNA processing, and/or nuclear organization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.