Evidence map›Paper›PMID 17123956›Full record

ArticleRNA (New York, N.Y.)2007

KISS: the kinetoplastid RNA editing sequence search tool.

Torsten Ochsenreiter, Michael Cipriano, Stephen L Hajduk

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Guide RNA Repertoires in the Main Lineages ofFrontiers in cellular and infection microbiology · 2021
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Aminoacylating urzymes challenge the RNA world hypothesis.The Journal of biological chemistry · 2013
    Article
  16. Article
  17. Article
  18. Article
  19. Mitochondrial RNA processing in trypanosomes.Research in microbiology · 2011
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Torsten OchsenreiterJosephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, Massachusetts 02543, USA.
Michael Cipriano
Stephen L Hajduk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinetoplastid mitochondrial mRNA editing is a post-transcriptional process of uridine insertion and deletion. Editing is mediated by small RNA molecules termed guide RNAs (gRNAs). Most gRNAs are encoded by numerous small circular DNA minicircles, while the protein coding mitochondrial genes are encoded on a separate, larger genome called the maxicircle. In order to provide a workbench for the analysis of RNA editing in kinetoplastids and a well-annotated set of guide RNAs for Trypanosoma brucei, we generated the kinetoplastid RNA editing sequence search tool (KISS) (http://gmod.mbl.edu/kiss/). KISS is a pipeline and database that uses BLAST comparisons and minicircle sequence motifs to annotate potential gRNAs and cognate mRNA editing sequence. KISS 1.0 contains all previously known minicircle and maxicircle data from Trypanosoma brucei plus >400 new minicircle sequences. Using an online format, KISS 1.0 allows the mapping and visualization of all known T. brucei gRNAs to minicircle genes and to potential mRNA substrates for RNA editing.

Indexed as

Databases, Nucleic AcidRNA EditingAnimalsBase SequenceComputational BiologyInternetKinetoplastidaRNA, Guide, KinetoplastidaRNA, ProtozoanSequence Analysis, RNATrypanosoma brucei bruceiRNA, Guide, KinetoplastidaRNA, Protozoan

Identifiers

PMID17123956
PMCPMC1705751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.