ArticleMycopathologia2006
Serologic testing for symptomatic coccidioidomycosis in immunocompetent and immunosuppressed hosts.
Article in Mycopathologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.
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- Coccidioidal Meningitis in an Immunocompetent Patient: A Rare Central Nervous System Infection.Cureus · 2026Article
- Fungal diagnostic stewardship in immunocompromised populations: a focus on molds and dimorphic fungi.Clinical microbiology reviews · 2026Review
- Role of Blastomyces BAD-1 IgG Enzyme Immunoassay (EIA) for the diagnosis of blastomycosis in persons residing in an endemic area.Medical mycology · 2026Article
- Practical Guidance for Clinical Microbiology Laboratories: Antibody and antigen detection methods for dimorphic fungal infections.Clinical microbiology reviews · 2025Review
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- Biomarkers in pulmonary infections: a clinical approach.Annals of intensive care · 2024Review
- Coccidioides Serologic Screening Practices in Individuals With Rheumatic and Autoimmune Diseases.ACR open rheumatology · 2024Article
- Challenges Facing Antimicrobial Stewardship Programs in the Endemic Region for Coccidioidomycosis.Open forum infectious diseases · 2024Review
- The Known and Unknown "Knowns" of Human Susceptibility to Coccidioidomycosis.Journal of fungi (Basel, Switzerland) · 2024Review
- Unexpected coccidioidomycosis presenting as lung nodules with presumptive diagnosis of malignancy.Clinical case reports · 2023Article
- Development of a rapid lateral flow assay for detection of anti-coccidioidal antibodies.Journal of clinical microbiology · 2023Article
- Spinal Infections Caused byMaedica · 2023Article
- Review of Clinical and Laboratory Diagnostics for Coccidioidomycosis.Journal of clinical microbiology · 2023Review
- Diagnostic Approach to Coccidioidomycosis in Solid Organ Transplant Recipients.Journal of fungi (Basel, Switzerland) · 2023Review
- A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS.IDCases · 2023Article
- Clinical Laboratory Utility of a Humanized Antibody in Commercially Available Enzyme Immunoassays for Coccidioidomycosis.Microbiology spectrum · 2022Article
- The Utility of (1→3)-β-D-Glucan Testing in the Diagnosis of Coccidioidomycosis in Hospitalized Immunocompromised Patients.Journal of fungi (Basel, Switzerland) · 2022Article
- Update on the Epidemiology, Diagnosis, and Treatment of Coccidioidomycosis.Journal of fungi (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serologic studies are an important diagnostic tool in the clinical evaluation and follow-up of persons with coccidioidomycosis. Numerous types of serologic tests are available, including immunodiffusion, enzyme immunoassay, and complement fixation. We conducted a retrospective review of the results of 1,797 serologic tests spanning 12 months from the onset of coccidioidomycosis in 298 immunocompetent and 62 immunosuppressed persons with symptomatic infection. Using the onset of symptoms as a reference point, we plotted the positive or negative serologic results over time for both groups. Compared with the immunocompetent group, immunosuppressed persons had lower rates of seropositivity for every type of test during the first year after onset of symptoms for coccidioidomycosis, although many results did not achieve statistical significance. Combining the results of these tests increased the sensitivity of the serologic evaluation in immunocompromised patients. Immunosuppressed persons have the ability to mount a serologic response to coccidioidomycosis, but in some circumstances, multiple methods may be required to improve detection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.