Evidence map›Paper›PMID 17121998›Full record

ArticleJournal of clinical microbiology2007

PCR-based diagnosis of Naegleria sp. infection in formalin-fixed and paraffin-embedded brain sections.

Marc Schild, Christian Gianinazzi, Bruno Gottstein, Norbert Müller

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Detection and Confirmation ofJournal of parasitology research · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Cardiac involvement with parasitic infections.Clinical microbiology reviews · 2010
    Review
  15. Diagnosis of infections caused by pathogenic free-living amoebae.Interdisciplinary perspectives on infectious diseases · 2009
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Surveillance and Molecular Identification ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marc SchildInstitute of Parasitology, University of Berne, Länggass-Strasse 122, CH-3012 Bern, Switzerland.
Christian Gianinazzi
Bruno Gottstein
Norbert Müller

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a real-time PCR which allowed the highly sensitive detection of Naegleria fowleri in histological brain tissue sections from experimentally infected mice. This genus-specific small-subunit (18S) rRNA gene-based PCR can complement conventional (immuno-) histology for the diagnosis of primary amoebic meningoencephalitis in paraffin-embedded brain necropsy specimens that had been fixed in formalin buffered with phosphate-buffered saline.

Indexed as

AmebiasisAnimalsBrainDNA, ProtozoanFixativesFormaldehydeMeningoencephalitisMiceMice, Inbred C57BLNaegleria fowleriParaffin EmbeddingPolymerase Chain ReactionTissue FixationDNA, ProtozoanFixativesFormaldehyde

Identifiers

PMID17121998
PMCPMC1828997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.