ReviewJournal of molecular medicine (Berlin, Germany)2007
CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction.
Review in Journal of molecular medicine (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 64 citations in OpenAlex.
- Shengmai San Ameliorates High-Glucose-Induced Calcium Homeostasis Imbalance via Improving Energy Metabolism in Neonatal Rat Cardiomyocytes.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Multipoint Left Ventricular Pacing as Alternative Approach in Cases of Biventricular Pacing Failure.Journal of clinical medicine · 2025Review
- An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.Science translational medicine · 2023Article
- Anti-inflammatory effects of endothelin receptor blockade in left atrial tissue of spontaneously hypertensive rats.International journal of cardiology. Heart & vasculature · 2022Article
- A Novel Insight Into the Fate of Cardiomyocytes in Ischemia-Reperfusion Injury: From Iron Metabolism to Ferroptosis.Frontiers in cell and developmental biology · 2021Review
- Cardioprotection of an IAmerican journal of translational research · 2021Article
- Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy.PLoS computational biology · 2020Article
- Partners in crime: POPX2 phosphatase and its interacting proteins in cancer.Cell death & disease · 2020Review
- Saponins in Chinese Herbal Medicine Exerts Protection in Myocardial Ischemia-Reperfusion Injury: Possible Mechanism and Target Analysis.Frontiers in pharmacology · 2020Review
- Targeting Calcium Homeostasis in Myocardial Ischemia/Reperfusion Injury: An Overview of Regulatory Mechanisms and Therapeutic Reagents.Frontiers in pharmacology · 2020Review
- Article
- IFrontiers in pharmacology · 2019Article
- MicroRNA Expression Profiling Screen miR-3557/324-TargetedBioMed research international · 2019Article
- Beneficial effects of leptin treatment in a setting of cardiac dysfunction induced by transverse aortic constriction in mouse.The Journal of physiology · 2017Article
- Transient outward potassium channel: a heart failure mediator.Heart failure reviews · 2015Review
- Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers.Nature communications · 2014Article
- Atrial fibrillation therapy now and in the future: drugs, biologicals, and ablation.Circulation research · 2014Review
- Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy.Nature reviews. Cardiology · 2012Review
- Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.The Journal of biological chemistry · 2012Article
- Basic science of cardiac resynchronization therapy: molecular and electrophysiological mechanisms.Circulation. Arrhythmia and electrophysiology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Maintenance of cytoplasmic calcium homeostasis is critical for all cells. An exciting field has emerged in elucidating the multiple roles that Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays in regulating Ca(2+) cycling in normal cardiac myocytes and in pathophysiological states. Moreover, CaMKII was recently identified as a potential drug target in cardiac disease. This work has given us a closer view of the complexity and therapeutic possibilities of CaMKII regulation of Ca(2+) signaling in cardiac myocytes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.