Evidence map›Paper›PMID 17119884›Full record

ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2006

[Response prediction--early response evaluation. Consequences for surgical oncology].

J R Siewert, F Lordick

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Gastric cancer and adenocarcinoma of the esophagogastric junction: principles of neoadjuvant therapy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011
    Review
  2. [Principles of neoadjuvant therapy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2009
    Review
  3. [Lymphadenectomy with tumors of the upper gastrointestinal tract].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J R SiewertChirurgische Klinik, Klinikum rechts der Isar, Technische Universität, Ismaninger Strasse 22, 81675, München, Deutschland. siewert@chir.med.tu-muenchen.de
F Lordick

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Response to perioperative chemotherapy or chemoradiation can hardly be predicted on the basis of molecular marker analyses. In contrast, by means of metabolic and molecular imaging using positron emission tomography, response can be assessed as early as 14 days after the start chemotherapy for many tumors. There is no doubt that the prognosis of patients with surgically resected tumors is much better in the case of a response to chemotherapy or chemoradiation. Important consequences can be deduced from this regarding the indications for perioperative therapies, the radicality of surgery or the surgical indications per se. In the following, we delineate the current knowledge on response prediction and early response evaluation in selected tumor entities and draw possible conclusions for clinical practice and future clinical studies.

Indexed as

Neoadjuvant TherapyAntineoplastic AgentsClinical Trials as TopicCombined Modality TherapyGastrointestinal NeoplasmsHumansNeoplasm StagingPositron-Emission TomographyPrognosisSurvival RateTomography, X-Ray ComputedAntineoplastic Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.