ArticleBioinformatics (Oxford, England)2007
NvMap: automated analysis of NMR chemical shift perturbation data.
Article in Bioinformatics (Oxford, England), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Harmonizing Peak Matching between Multidimensional NMR Spectra.Journal of chemical information and modeling · 2026Article
- Fully Automated Characterization of Protein-Peptide Binding by Microfluidic 2D NMR.Journal of the American Chemical Society · 2023Article
- Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server.Journal of chemical information and modeling · 2021Article
- Introducing the CSP Analyzer: A novel Machine Learning-based application for automated analysis of two-dimensional NMR spectra in NMR fragment-based screening.Computational and structural biotechnology journal · 2020Article
- Automation of peak-tracking analysis of stepwise perturbed NMR spectra.Journal of biomolecular NMR · 2017Article
- Combining automated peak tracking in SAR by NMR with structure-based backbone assignment from 15N-NOESY.BMC bioinformatics · 2012Article
- Identification of SUMO-binding motifs by NMR.Methods in molecular biology (Clifton, N.J.) · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
unlabelledNMR chemical shift perturbation experiments are widely used to define binding sites in biomolecular complexes. Especially in the case of high throughput screening of ligands, rapid analysis of NMR spectra is essential. NvMap extends NMRViewJ and provides a means for rapid assignments and book-keeping of NMR titration spectra. Our module offers options to analyze multiple titration spectra both separately and sequentially, where the sequential spectra are analyzed either two at a time or all simultaneously. The first option is suitable for slow or intermediate exchange rates between free and bound proteins. The latter option is particularly useful for fast exchange situations and can compensate for the lack of indicators for overlapped peaks. Our module also provides a simple user interface to automate the analysis process from dataset to peak list. We demonstrate the effectiveness of our program using NMR spectra of SUMO in complexes with three different peptides. AVAILABILITY: NvMap is available on the web at http://www.cityofhope.org/Researchers/ChenYuan/NvMap/ Supplemental information: Manual pages and test spectra will be available on the web at the above site.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.