ArticleSexually transmitted infections2006
A multi-centre evaluation of nine rapid, point-of-care syphilis tests using archived sera.
Article in Sexually transmitted infections, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Evaluation of rapid diagnostic test kits for detection of Treponema pallidum antibody.PloS one · 2024Article
- Facilitators and barriers to point-of-care testing for sexually transmitted infections in low- and middle-income countries: a scoping review.BMC infectious diseases · 2022Article
- Community Health Impacts of the Trident Copper Mine Project in Northwestern Zambia: Results from Repeated Cross-Sectional Surveys.International journal of environmental research and public health · 2020Article
- Evaluation of the utility of a rapid test for syphilis at a sexually transmitted disease clinic in Buenos Aires, Argentina.Scientific reports · 2018Article
- Expanding syphilis testing: a scoping review of syphilis testing interventions among key populations.Expert review of anti-infective therapy · 2018Article
- Selected indicators and determinants of women's health in the vicinity of a copper mine development in northwestern Zambia.BMC women's health · 2018Article
- Field evaluation of SD BIOLINE HIV/Syphilis Duo assay among pregnant women attending routine antenatal care in Juba, South Sudan.PloS one · 2018Article
- Evaluation of a Rapid Immunochromatographic Treponemal Antibody Test Comparing the Treponema Pallidum Particle Agglutination Assay.Journal of clinical laboratory analysis · 2015Article
- Evaluation of the diagnostic performance and operational characteristics of four rapid immunochromatographic syphilis tests in Burkina Faso.African health sciences · 2015Article
- Syphilis testing in blood donors: an update.Blood transfusion = Trasfusione del sangue · 2015Review
- Recent trends in the serologic diagnosis of syphilis.Clinical and vaccine immunology : CVI · 2015Review
- Evaluation of two commercially available rapid diagnostic tests for Lyme borreliosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Article
- Current trends in donor testing to detect syphilis infection.Current infectious disease reports · 2014Article
- Multisite Laboratory Evaluation of a Dual Human Immunodeficiency Virus (HIV)/Syphilis Point-of-Care Rapid Test for Simultaneous Detection of HIV and Syphilis Infection.Open forum infectious diseases · 2014Article
- The endemic treponematoses.Clinical microbiology reviews · 2014Review
- Sensitivity and specificity of point-of-care rapid combination syphilis-HIV-HCV tests.PloS one · 2014Article
- Article
- A dual point-of-care test shows good performance in simultaneously detecting nontreponemal and treponemal antibodies in patients with syphilis: a multisite evaluation study in China.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Article
- Rapid-Testing Technology and Systems Improvement for the Elimination of Congenital Syphilis in Haiti: Overcoming the "Technology to Systems Gap".Journal of sexually transmitted diseases · 2013Article
- Advances in the diagnosis of endemic treponematoses: yaws, bejel, and pinta.PLoS neglected tropical diseases · 2013Review
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate nine rapid syphilis tests at eight geographically diverse laboratory sites for their performance and operational characteristics.
methodsTests were compared "head to head" using locally assembled panels of 100 archived (50 positive and 50 negative) sera at each site using as reference standards the Treponema pallidum haemagglutination or the T pallidum particle agglutination test. In addition inter-site variation, result stability, test reproducibility and test operational characteristics were assessed.
resultsAll nine tests gave good performance relative to the reference standard with sensitivities ranging from 84.5-97.7% and specificities from 84.5-98%. Result stability was variable if result reading was delayed past the recommended period. All the tests were found to be easy to use, especially the lateral flow tests.
conclusionsAll the tests evaluated have acceptable performance characteristics and could make an impact on the control of syphilis. Tests that can use whole blood and do not require refrigeration were selected for further evaluation in field settings.
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Registered trials
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