Evidence map›Paper›PMID 17114265›Full record

ArticleJournal of bacteriology2007

Bacillus subtilis genome diversity.

Ashlee M Earl, Richard Losick, Roberto Kolter

Abstract read
In one paragraph

Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
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  4. Genome report of a probioticMicrobiology resource announcements · 2025
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  5. The extracytoplasmic sigma factor σScientific reports · 2025
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  7. ComI inhibits transformation inJournal of bacteriology · 2024
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  8. Article
  9. Genetic Evidences of Biosurfactant Production in TwoFrontiers in bioengineering and biotechnology · 2022
    Article
  10. Review
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  12. Prevalence of Wheat AssociatedFrontiers in microbiology · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Comparative Genome Characterization of a Petroleum-DegradingInternational journal of genomics · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ashlee M EarlDepartment of Microbiology & Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
Richard Losick
Roberto Kolter

Funding

MOLECULAR GENETICS OF BIOFILM FORMATIONR01GM058213 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RUDNER, DAVID Z · 1998 to 2017
$7.5M
Extracellular Matrix of Bacillus subtilis BiofilmsF32GM072393 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI EARL, ASHLEE MIRIAM · 2004 to 2007
$142k
NIGMS NIH HHS F32 GM072393NIGMS NIH HHS GM072393NIGMS NIH HHS GM58213NIGMS NIH HHS R01 GM058213
6 · The paper itself

Abstract

Microarray-based comparative genomic hybridization (M-CGH) is a powerful method for rapidly identifying regions of genome diversity among closely related organisms. We used M-CGH to examine the genome diversity of 17 strains belonging to the nonpathogenic species Bacillus subtilis. Our M-CGH results indicate that there is considerable genetic heterogeneity among members of this species; nearly one-third of Bsu168-specific genes exhibited variability, as measured by the microarray hybridization intensities. The variable loci include those encoding proteins involved in antibiotic production, cell wall synthesis, sporulation, and germination. The diversity in these genes may reflect this organism's ability to survive in diverse natural settings.

Indexed as

Genetic VariationGenome, BacterialBacillus subtilisBacterial ProteinsGenes, BacterialNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisPhylogenySpecies SpecificityBacterial Proteins

Identifiers

PMID17114265
PMCPMC1797320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.