Evidence map›Paper›PMID 17113784›Full record

ReviewSeminars in cancer biology2007

MicroRNAs and genomic instability.

Konrad Huppi, Natalia Volfovsky, Mark Mackiewicz, Timothy Runfola, Tamara L Jones, Scott E Martin, Robert Stephens, Natasha J Caplen

Registry-linked trialAbstract readReview
In one paragraph

Review in Seminars in cancer biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02009852 (The Role of microRNA-29b in the Oral Squamous Cell Carcinoma), which is not on this map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02009852 unknown statusnot on this mapstarted 2014, after this paper: background citation

The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

Typeobservational_patient_registrySponsorNational Taiwan University HospitalRan2014Enrolled100ConditionsOral Cancer
3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. MicroRNAs and metabolic disorders - where are we heading?Archives of medical science : AMS · 2017
    Article
  11. Biomarkers of genome instability and cancer epigenetics.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  12. Article
  13. Article
  14. Article
  15. Challenges and opportunities of microRNAs in lymphomas.Molecules (Basel, Switzerland) · 2014
    Review
  16. Article
  17. microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013
    Article
  18. Article
  19. Article
  20. The role of microRNAs in lung cancer progression.Medical oncology (Northwood, London, England) · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Konrad HuppiGene Silencing Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. huppi@helix.nih.gov
Natalia Volfovsky
Mark Mackiewicz
Timothy Runfola
Tamara L Jones
Scott E Martin
Robert Stephens
Natasha J Caplen

Funding

The Role of miRNA-mediated RNAI in the Biology of CancerZ01BC010612 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CAPLEN, NATASHA · 2005 to 2008
$691k
Intramural NIH HHS Z01 BC010612
6 · The paper itself

Abstract

A new species of non-coding RNA, microRNAs (miRNAs) has been identified that may regulate the expression of as many as one third to one half of all protein encoding genes. MicroRNAs are found throughout mammalian genomes, but an association between the location of these miRNAs and regions of genomic instability (or fragile sites) in humans has been suggested [1]. In this review we discuss the possible role of altered miRNA expression on human cancer and conduct an analysis correlating the physical location of murine miRNAs with sites of genetic alteration in mouse models of cancer.

Indexed as

Genomic InstabilityMicroRNAsAnimalsComputational BiologyDNA, NeoplasmGene Expression ProfilingGenomeGenome, HumanHumansMiceModels, BiologicalModels, GeneticMultigene FamilyNeoplasmsRNADNA, NeoplasmMicroRNAsRNA

Identifiers

PMID17113784
PMCPMC1839944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.