ArticleSurgical endoscopy2007
Routine laparoscopic cholecystectomy after endoscopic sphincterotomy for choledocholithiasis in octogenarians: is it worth the risk?
Article in Surgical endoscopy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07001423 (ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- One-Stage Intraoperative ERCP combined with Laparoscopic Cholecystectomy Versus Two-Stage Preoperative ERCP Followed by Laparoscopic Cholecystectomy in the Management of Gallbladder with Common Bile Duct Stones: A Meta-analysis.Advances in therapy · 2024Pooled it
- Prophylactic cholecystectomy offers best outcomes following ERCP clearance of common bile duct stones: a meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Perioperative outcomes after laparoscopic cholecystectomy in elderly patients: a systematic review and meta-analysis.Surgical endoscopy · 2020Pooled it
- Pooled it
- The challenge of cholecystectomy after successful choledocholithiasis extraction in elderly patients with comorbidities.BMC surgery · 2025Article
- Delayed Cholecystectomy After ERCP in Geriatric Patients: Balancing Surgical Risk and Recurrence Prevention - A Retrospective Study.Clinical interventions in aging · 2025Article
- One-year outcomes of elderly acute cholecystitis patients by index treatment.Frontiers in surgery · 2025Article
- The role of cholecystectomy following endoscopic sphincterotomy and bile duct stone removal.Annals of the Royal College of Surgeons of England · 2023Article
- Which octogenarian patients are at higher risk after cholecystectomy for symptomatic gallstone disease? A single center cohort study.World journal of clinical cases · 2022Article
- Article
- Outcome of acute pancreatitis in octogenarians: A retrospective study.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Outcomes and risk factors of cholecystectomy in high risk patients: A case series.Annals of medicine and surgery (2012) · 2020Article
- Early laparoscopic cholecystectomy is associated with less risk of complications after the removal of common bile duct stones by endoscopic retrograde cholangiopancreatography.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- Laparoscopic common bile duct exploration; a preferential pathway for elderly patients.Annals of medicine and surgery (2012) · 2018Article
- Laparoscopic common bile duct exploration: a safe and definitive treatment for elderly patients.Surgical endoscopy · 2017Article
- Cholecystectomy after endoscopic papillary balloon dilation for bile duct stones reduced late biliary complications: a propensity score-based cohort analysis.Surgical endoscopy · 2016Article
- High rate of common bile duct stones and postoperative abscess following percutaneous cholecystostomy.Annals of the Royal College of Surgeons of England · 2016Article
- Diagnosis and management of choledocholithiasis in the golden age of imaging, endoscopy and laparoscopy.World journal of gastroenterology · 2014Review
- The fate of patients who undergo "preoperative" ERCP to clear known or suspected bile duct stones.Surgical endoscopy · 2009Article
- Laparo-endoscopic "Rendezvous" to treat cholecysto-choledocolithiasis: Effective, safe and simplifies the endoscopist's work.World journal of gastroenterology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo unanimous consensus has been reached as to the need for routine laparoscopic cholecystectomy (LC) after endoscopic sphincterotomy (ES) for choledocholithiasis in very elderly patients, who are considered as high-risk subjects for surgery.
methodsFrom 1991 through 1997, 170 patients were referred to undergo preoperative ES and routine LC for common bile duct (CBD) stones. The results for 27 patients (age 80 years or older) were compared with those achieved for younger patients. Successively, in a retrospective case-control study, the results for the selected patients were compared with those for 27 very elderly patients who underwent endoscopic retrograde cholangiopancreatography (ERCP), but did not receive LC. The mean follow-up period was 126 months.
resultsOctogenarians showed longer surgery time (79 vs 51 min) and postoperative hospital stay (2.8 vs 1.2 days), as well as more early low-grade complications (15% vs 3%), whereas there were no differences in conversion rate or serious complications. Recurrent symptoms or complications developed in 48% of octogenarians not undergoing routine LC, and 30% finally needed surgery. One patient in the control group died after emergency cholecystectomy for acute cholecystitis. The results of surgery were significantly poorer for the control group.
conclusionsAlthough a "wait-and-see" policy allowed two-thirds of LCs to be avoided in octogenarians, biliary-related events developed for every second patient, often requiring delayed surgery, with poorer results. Sequential treatment (ES followed by elective LC) is a safe procedure for octogenarians, and should be considered as a standard, definitive treatment for cholecystocholedocholithiasis even after the age of 80 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.