Evidence map›Paper›PMID 17111227›Full record

ArticleJournal of fluorescence2007

Microporated PEG spheres for fluorescent analyte detection.

Rebecca M Rounds, Bennett L Ibey, Hope T Beier, Michael V Pishko, Gerard L Coté

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Injectable hydrogel microbeads for fluorescence-based in vivo continuous glucose monitoring.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
  10. Dissolved core alginate microspheres as "smart-tattoo" glucose sensors.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2009
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecca M RoundsDepartment of Biomedical Engineering, Texas A and M University, Mail Stop 3120, College Station, TX 77843, USA. becky.rounds@gmail.com
Bennett L Ibey
Hope T Beier
Michael V Pishko
Gerard L Coté

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(ethylene glycol) (PEG) hydrogels have been used to encapsulate fluorescently labeled molecules in order to detect a variety of analytes. The hydrogels are designed with a mesh size that will retain the sensing elements while allowing for efficient diffusion of small analytes. Some sensing assays, however, require a conformational change or binding of large macromolecules, which may be sterically prohibited in a dense polymer matrix. A process of hydrogel microporation has been developed to create cavities within PEG microspheres to contain the assay components in solution. This arrangement provides improved motility for large sensing elements, while limiting leaching and increasing sensor lifetime. Three hydrogel compositions, 100% PEG, 50% PEG, and microporated 100% PEG, were used to create pH-sensitive microspheres that were tested for response time and stability. In order to assess motility, a second, more complex sensor, namely a FITC-dextran/TRITC-Con A glucose-specific assay was encapsulated within the microspheres.

Indexed as

FluorescenceMicrospheresCapsulesConcanavalin ADextransFluorescein-5-isothiocyanateFluorescent DyesGlucoseHydrogelsHydrogen-Ion ConcentrationLectinsPolyethylene GlycolsPolymersPorosityRhodaminesSolutionsCapsulesConcanavalin ADextransFluorescein-5-isothiocyanateFluorescent DyesGlucoseHydrogelsLectinsPolyethylene GlycolsPolymersRhodaminesSolutionstetramethylrhodamine isothiocyanateWater

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.