Evidence map›Paper›PMID 17111223›Full record

ReviewJournal of mammary gland biology and neoplasia2006

Alveolar and lactogenic differentiation.

Cathrin Brisken, Renuga Devi Rajaram

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects ofFrontiers in veterinary science · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Development of the mammary glands and its regulation: how not all species are equal.Animal frontiers : the review magazine of animal agriculture · 2023
    Article
  10. Review
  11. Article
  12. Medicinal MushroomEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  13. Article
  14. Endocrine-disrupting chemicals and breastfeeding duration: a review.Current opinion in endocrinology, diabetes, and obesity · 2020
    Review
  15. Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Primary Mammary Organoid Model of Lactation and Involution.Frontiers in cell and developmental biology · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation.American journal of physiology. Endocrinology and metabolism · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Cathrin BriskenNational Center of Competence in Research (NCCR) Molecular Oncology, Swiss Institute for Experimental Cancer Research (ISREC), 155 Chemin des Boveresses, CH-1066, Epalinges, Lausanne, Switzerland. Cathrin.Brisken@isrec.ch
Renuga Devi Rajaram
École Polytechnique Fédérale de Lausanne · CHSwiss Institute of Comparative Law · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mouse mammary gland is a complex tissue that proliferates and differentiates under the control of systemic hormones during puberty, pregnancy and lactation. Once a highly branched milk duct system has been established, during mid/late pregnancy, alveoli, little saccular outpouchings, sprout all over the ductal system and differentiate to become the sites of milk secretion. Here, we review the emerging network of the signaling pathways that connects hormonal stimuli with locally produced signaling molecules and the components of intracellular pathways that regulate alveologenesis and lactation. The powerful tools of mouse genetics have been instrumental in uncovering many of the signaling components involved in controlling alveolar and lactogenic differentiation.

Indexed as

Cell DifferentiationLactationSignal TransductionAnimalsCell AdhesionFemaleHormonesMammary Glands, AnimalMiceMice, Mutant StrainsParacrine CommunicationHormones

Identifiers

PMID17111223
OpenAlexW2036148005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.