ArticleCell proliferation2006
Assessment of pluripotency and multilineage differentiation potential of NTERA-2 cells as a model for studying human embryonic stem cells.
Article in Cell proliferation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- NT2-derived astrocyte-neuron co-culture reflects physiological relevance and offers research validity.Cellular & molecular biology letters · 2025Article
- Exploring Novel Therapeutic Opportunities for Glioblastoma Using Patient-Derived Cell Cultures.Cancers · 2023Article
- A novel therapeutic approach using peripheral blood mononuclear cells preconditioned by oxygen-glucose deprivation.Scientific reports · 2019Article
- In vitro induction of human embryonal carcinoma differentiation by a crude extract of Rhazya stricta.BMC complementary and alternative medicine · 2017Article
- Mechanisms Regulating Stemness and Differentiation in Embryonal Carcinoma Cells.Stem cells international · 2017Review
- The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.Cancer research · 2016Article
- Crosstalk between SOXB1 proteins and WNT/β-catenin signaling in NT2/D1 cells.Histochemistry and cell biology · 2015Article
- An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.BMC genomics · 2014Article
- Embryonic carcinoma cells show specific dielectric resistance profiles during induced differentiation.PloS one · 2013Article
- Serine 111 phosphorylation regulates OCT4A protein subcellular distribution and degradation.The Journal of biological chemistry · 2012Article
- Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster.Nature communications · 2012Article
- Human first-trimester chorionic villi have a myogenic potential.Cell and tissue research · 2012Article
- Article
- Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons.PloS one · 2011Article
- Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.Stem cells (Dayton, Ohio) · 2010Article
- Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Embryonal carcinoma cells are pluripotent stem cells derived from teratocarcinomas and are considered to be the malignant counterparts of human embryonic stem cells. As there are few reliable experimental systems available to study the molecular mechanisms governing normal embryogenesis, well-characterized human embryonal carcinoma stem cell lines may provide a robust and simple model to study certain aspects of pluripotency and cellular differentiation. Here, we have analysed NTERA-2 cL.D1 cells at molecular and cellular levels during expansion and differentiation, via formation of cell aggregates similar to embryoid bodies in embryonic stem cells. Thus, human embryonal carcinoma cells may provide a valuable insight into cell fate determination, into the embryonic ectoderm, mesoderm and endoderm and their downstream derivatives.
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