ArticleInternational journal of colorectal disease2007
Pulmonary resection for metastases from colorectal cancer: prognostic factors and survival.
Article in International journal of colorectal disease, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03517618 (A Phase II Study Assessing Efficacy and Safety of TS-1 in Combination With Calcium Folinate in Patients With Heavily Pre-treated Metastatic Colorectal Cancer), which is not on this map. Cited by 70 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase II Study Assessing Efficacy and Safety of TS-1 in Combination With Calcium Folinate in Patients With Heavily Pre-treated Metastatic Colorectal Cancer
Who cites it
70 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Clinical Efficacy of Colorectal Cancer Patients with Pulmonary Oligometastases by Sterotactic Body Ablative Radiotherapy: A Meta-Analysis.Cancer research and treatment · 2024Pooled it
- Tumor Control and Overall Survival after Stereotactic Body Radiotherapy for Pulmonary Oligometastases from Colorectal Cancer: A Meta-Analysis.Cancer research and treatment · 2020Pooled it
- Pooled it
- Follow-up strategies for patients treated for non-metastatic colorectal cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Follow-up strategies for patients treated for non-metastatic colorectal cancer.The Cochrane database of systematic reviews · 2016Pooled it
- Prognostic impact of tumor size on patients with metastatic colorectal cancer: a large SEER-based retrospective cohort study.Updates in surgery · 2023Trial
- Peri-operative chemotherapy in the management of resectable colorectal cancer pulmonary metastases.BMC cancer · 2012Trial
- Prognostic factors after pulmonary metastasectomy for colorectal cancer lung metastasis.Lung India : official organ of Indian Chest Society · 2026Article
- Pulmonary Metastasectomy for Colorectal Cancer: Evidence and Outcomes-A Narrative Review.Journal of clinical medicine · 2025Review
- The Ugly: Metastatic Colon Cancer-Surgical Options.Clinics in colon and rectal surgery · 2025Review
- Prognostic significance of lymph nodes assessment during pulmonary metastasectomy: a systematic review and meta-analysis.Journal of thoracic disease · 2023Article
- Review
- The İmportance of tumor markers in patients undergoing resection for lung metastasis of colorectal carcinoma.The clinical respiratory journal · 2023Article
- Neoadjuvant Versus Adjuvant Chemotherapy for Resectable Metastatic Colon Cancer in Non-academic and Academic Programs.The oncologist · 2023Article
- Review
- A Radiomics Approach on Chest CT Distinguishes Primary Lung Cancer from Solitary Lung Metastasis in Colorectal Cancer Patients.Journal of personalized medicine · 2022Article
- Management of single pulmonary metastases from colorectal cancer: State of the art.World journal of gastrointestinal oncology · 2022Review
- Risk factors for venous thromboembolism in metastatic colorectal cancer with contemporary treatment: A SEER-Medicare analysis.Cancer medicine · 2022Article
- A novel diagnostic model for differentiation of lung metastasis from primary lung cancer in patients with colorectal cancer.Frontiers in oncology · 2022Article
- Effects of the number of neoadjuvant therapy cycles on clinical outcomes, safety, and survival in patients with metastatic colorectal cancer undergoing metastasectomy.Oncology research · 2022Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary metastases occur in up to 10% of all patients who undergo curative resection. Surgical resection is an important part in the treatment of pulmonary metastasis from colorectal cancer. We analyzed the treatment outcome and prognostic factors affecting survival in this subset of patients. MATERIALS AND
methodsBetween October 1994 and December 2004, 59 patients underwent curative resection for pulmonary metastases of colorectal cancer. Uncontrollable synchronous liver and lung metastasis or synchronous colorectal cancer with isolated lung metastasis were excluded from this study. A retrospective review of patient characteristics and factors influencing survival was performed. Survival was analyzed by the Kaplan-Meier method. Comparison between groups were performed by a log-rank analysis and the Cox proportional hazard model.
resultsThe 5-year overall survival rate of all patients who received pulmonary resection was 50.3%. The number of pulmonary metastases was significantly related with survival in univariate analysis, but not in multivariate analysis (p = 0.032). Prethoracotomy carcinoembryonic antigen (CEA) level exceeding 5 ng/ml was related with poor survival (p = 0.001). A disease-free interval of greater than 2 years did not correlate with survival after thoracotomy (p = 0.3).
conclusionThe prethoracotomy CEA level and the number of metastases were independent prognostic factors. Resection of pulmonary metastasis from colorectal cancer may result in improved survival or even healing in selected patients. Pulmonary resection of colorectal cancer is regarded as a safe and effective treatment with low morbidity and mortality rates.
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