ReviewNature reviews. Microbiology2006
Why do we need quality-assured diagnostic tests for sexually transmitted infections?
Review in Nature reviews. Microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Pooled it
- Pooled it
- Article
- Droplet-Based Measurements of DNA-Templated Nanoclusters-Towards Point-of-Care Applications.Biosensors · 2025Article
- Point-of-care COVID-19 diagnostics powered by lateral flow assay.Trends in analytical chemistry : TRAC · 2021Review
- Plasma Isolation in a Syringe by Conformal Integration of Inertial Microfluidics.Annals of biomedical engineering · 2021Article
- Development of a Flow-Free Automated Colorimetric Detection Assay Integrated with Smartphone for Zika NS1.Diagnostics (Basel, Switzerland) · 2020Article
- E-DNA scaffold sensors and the reagentless, single-step, measurement of HIV-diagnostic antibodies in human serum.Microsystems & nanoengineering · 2020Article
- A rapid smartphone-based lactate dehydrogenase test for neonatal diagnostics at the point of care.Scientific reports · 2019Article
- Surveillance of intestinal schistosomiasis during control: a comparison of four diagnostic tests across five Ugandan primary schools in the Lake Albert region.Parasitology · 2018Article
- HCV Detection, Discrimination, and Genotyping Technologies.Sensors (Basel, Switzerland) · 2018Review
- Evaluation of antenatal rapid human immunodeficiency virus testing in rural South Africa.Southern African journal of HIV medicine · 2018Article
- Point-of-Care Diagnostics for Improving Maternal Health in South Africa.Diagnostics (Basel, Switzerland) · 2016Review
- Poor Performance of the Chlamydia Rapid Test Device for the Detection of Asymptomatic Infections in South African Men: A Pilot Study.Journal of sexually transmitted diseases · 2016Article
- Advances in plasmonic technologies for point of care applications.Chemical reviews · 2014Review
- Micro-a-fluidics ELISA for rapid CD4 cell count at the point-of-care.Scientific reports · 2014Article
- Article
- Poor Reporting of Outcomes Beyond Accuracy in Point-of-Care Tests for Syphilis: A Call for a Framework.AIDS research and treatment · 2014Review
- Improving access to new diagnostics through harmonised regulation: priorities for action.African journal of laboratory medicine · 2014Article
- Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy.Microbes and infection · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bacterial sexually transmitted infections (STIs) syphilis, gonorrhoea and chlamydia can all be cured with a single dose of antibiotic. Unfortunately, however, these infections often remain undiagnosed as many infected individuals have few if any symptoms. Diagnostic tests with high sensitivity and specificity are available for all three infections but, owing to their expense and the lack of laboratory capacity, most people in developing countries do not have access to these tests. There is a great need for simple, cheap diagnostic tests for STIs that can be performed at the point of care, enabling treatment to be given immediately. It is hoped that recent advances in our understanding of the pathogenesis of these infections, and the availability of the complete genome sequences for each causative organism, will lead to the development of improved point-of-care tests that will reduce the burden of these diseases in developing countries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.