ArticleNucleic acids research2007
The ASAP II database: analysis and comparative genomics of alternative splicing in 15 animal species.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed.
- Semi-quantitative RT-PCR Assay for the Analysis of Alternative Splicing of Interleukin Genes.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Alternative splicing across the tree of life.eLife · 2025Article
- Mechanistic Insights into Alternative Gene Splicing in Oxidative Stress and Tissue Injury.Antioxidants & redox signaling · 2024Review
- Functional analysis of theAnimal biotechnology · 2024Article
- Interplays betweenInternational journal of molecular sciences · 2023Article
- F1 Male Sterility in Cattle-Yak Examined through Changes in Testis Tissue and Transcriptome Profiles.Animals : an open access journal from MDPI · 2022Article
- Gene co-expression and alternative splicing analysis of key metabolic tissues to unravel the regulatory signatures of fatty acid composition in cattle.RNA biology · 2021Article
- Genome-wide profiling of alternative splicing genes in hybrid poplar (P.alba×P.glandulosa cv.84K) leaves.PloS one · 2020Article
- Comparative analysis of the accelerated aged seed transcriptome profiles of two maize chromosome segment substitution lines.PloS one · 2019Article
- Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles.BMC genomics · 2018Article
- ASpedia: a comprehensive encyclopedia of human alternative splicing.Nucleic acids research · 2018Article
- A spectrum of modularity in multi-functional gene circuits.Molecular systems biology · 2017Article
- Identification of a large intronic transposal insertion in SLC17A5 causing sialic acid storage disease.Orphanet journal of rare diseases · 2017Article
- Alternative splicing and the evolution of phenotypic novelty.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond.Briefings in bioinformatics · 2016Article
- MiasDB: A Database of Molecular Interactions Associated with Alternative Splicing of Human Pre-mRNAs.PloS one · 2016Article
- Deep RNA sequencing reveals a high frequency of alternative splicing events in the fungus Trichoderma longibrachiatum.BMC genomics · 2015Article
- Fungal alternative splicing is associated with multicellular complexity and virulence: a genome-wide multi-species study.DNA research : an international journal for rapid publication of reports on genes and genomes · 2014Article
- Article
- Function of alternative splicing.Gene · 2013Review
5 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
We have greatly expanded the Alternative Splicing Annotation Project (ASAP) database: (i) its human alternative splicing data are expanded approximately 3-fold over the previous ASAP database, to nearly 90,000 distinct alternative splicing events; (ii) it now provides genome-wide alternative splicing analyses for 15 vertebrate, insect and other animal species; (iii) it provides comprehensive comparative genomics information for comparing alternative splicing and splice site conservation across 17 aligned genomes, based on UCSC multigenome alignments; (iv) it provides an approximately 2- to 3-fold expansion in detection of tissue-specific alternative splicing events, and of cancer versus normal specific alternative splicing events. We have also constructed a novel database linking orthologous exons and orthologous introns between genomes, based on multigenome alignment of 17 animal species. It can be a valuable resource for studies of gene structure evolution. ASAP II provides a new web interface enabling more detailed exploration of the data, and integrating comparative genomics information with alternative splicing data. We provide a set of tools for advanced data-mining of ASAP II with Pygr (the Python Graph Database Framework for Bioinformatics) including powerful features such as graph query, multigenome alignment query, etc. ASAP II is available at http://www.bioinformatics.ucla.edu/ASAP2.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.