ArticleJournal of clinical microbiology2007
Analysis of changes in recent tuberculosis transmission patterns after a sharp increase in immigration.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Molecular clustering of patients with diabetes and pulmonary tuberculosis: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Tuberculosis transmission between foreign- and native-born populations in the EU/EEA: a systematic review.The European respiratory journal · 2014Pooled it
- Genotyping and spatial analysis of pulmonary tuberculosis and diabetes cases in the state of Veracruz, Mexico.PloS one · 2018Article
- Genetic diversity of Mycobacterium tuberculosis isolates from Tochigi prefecture, a local region of Japan.BMC infectious diseases · 2017Article
- Frequency of infectious diseases in immigrants in a Western European country: a population-based study.Journal of immigrant and minority health · 2015Article
- Role of casual contacts in the recent transmission of tuberculosis in settings with high disease burden.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2014Article
- Clustering of tuberculosis cases based on variable-number tandem-repeat typing in relation to the population structure of Mycobacterium tuberculosis in the Netherlands.Journal of clinical microbiology · 2013Article
- Impact of immigration on burden of tuberculosis in Umbria: a low-incidence Italian region with high immigrants rates.Journal of preventive medicine and hygiene · 2013Article
- Tuberculosis transmission among immigrants and autochthonous populations of the eastern province of Saudi Arabia.PloS one · 2013Article
- Epidemiology of tuberculosis in a low-incidence Italian region with high immigration rates: differences between not Italy-born and Italy-born TB cases.BMC public health · 2011Article
- Impact of immigration on the molecular epidemiology of tuberculosis in Rhode Island.Journal of clinical microbiology · 2011Article
- Transmission dynamics of pulmonary tuberculosis between autochthonous and immigrant sub-populations.BMC infectious diseases · 2009Article
- Imported infectious diseases in mobile populations, Spain.Emerging infectious diseases · 2009Article
- Conjunctivitis with regional lymphadenopathy in a trainee microbiologist.Journal of clinical microbiology · 2009Article
- Prospective universal application of mycobacterial interspersed repetitive-unit-variable-number tandem-repeat genotyping to characterize Mycobacterium tuberculosis isolates for fast identification of clustered and orphan cases.Journal of clinical microbiology · 2009Article
- Ethical considerations about reporting research results with potential for further stigmatization of undocumented immigrants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2009Article
- Differences in clinical presentation among persons with pulmonary tuberculosis: a comparison of documented and undocumented foreign-born versus US-born persons.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2008Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a population-based molecular epidemiological study of tuberculosis (TB) in Madrid, Spain (2002 to 2004), to define transmission patterns and factors associated with clustering. We particularly focused on examining how the increase in TB cases among immigrants in recent years (2.8% in 1997 to 1999 to 36.2% during the current study) was modifying transmission patterns. Mycobacterium tuberculosis isolates obtained from patients living in nine districts of Madrid (1,459,232 inhabitants) were genotyped. The TB case rate among foreign-born people was three to four times that of Spanish-born people, and the median time from arrival to the onset of treatment was 22.4 months. During the study period, 227 (36.3%) patients were grouped in 64 clusters, and 115 (50.7%) of them were in 21 clusters with mixed Spanish-born and foreign-born patients. Three of the 21 mixed clusters accounted for 21.1% of clustered patients. Twenty-two of 38 (57.9%) immigrants in mixed clusters were infected with TB strains that had already been identified in the native population in 1997 to 1999, including the three most prevalent strains. Factors identified as independent predictors of clustering were homelessness (odds ratio [OR], 2.3; 95% confidence interval [95% CI], 1.2 to 4.5; P = 0.011) and to be born in Spain (OR, 1.8; 95% CI, 1.2 to 2.6; P = 0.002). The results indicated that (i) TB transmission was higher in Spanish-born people, associated mainly with homelessness, (ii) that foreign-born people were much less likely to be clustered, suggesting a higher percentage of infection before arriving in Spain, and (iii) that an extensive transmission between Spanish- and foreign-born populations, caused mainly by autochthonous strains, was taking place in Madrid.
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