ReviewEnvironmental health perspectives2006
Polybrominated diphenyl ethers: a case study for using biomonitoring data to address risk assessment questions.
Review in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Opportunities in Assessing and Regulating Organohalogen Flame Retardants (OFRs) as a Class in Consumer Products.Environmental health perspectives · 2024Article
- A meta-analysis of randomized controlled studies on the hepatoxicity induced by polybrominated diphenyl ethers (PBDEs) in rats and mice.Current research in toxicology · 2023Article
- Placenta Disrupted: Endocrine Disrupting Chemicals and Pregnancy.Trends in endocrinology and metabolism: TEM · 2020Review
- Polybrominated diphenyl ethers (PBDEs) in core sediments from creek ecosystem: occurrence, geochronology, and source contribution.Environmental geochemistry and health · 2018Article
- Temporal Evaluation of Polybrominated Diphenyl Ether (PBDE) Serum Levels in Middle-Aged and Older California Women, 2011-2015.Environmental science & technology · 2017Article
- Predictors of Serum Polybrominated Diphenyl Ether (PBDE) Concentrations among Children Aged 1-5 Years.Environmental science & technology · 2017Article
- Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2017Article
- Serum polybrominated diphenyl ether concentrations and thyroid function in young children.Environmental research · 2016Article
- Approaches to Children's Exposure Assessment: Case Study with Diethylhexylphthalate (DEHP).International journal of environmental research and public health · 2016Review
- Role of environmental contaminants in the etiology of Alzheimer's disease: a review.Current Alzheimer research · 2015Review
- Residential levels of polybrominated diphenyl ethers and risk of childhood acute lymphoblastic leukemia in California.Environmental health perspectives · 2014Article
- Developmental Exposure to Polybrominated Diphenyl Ethers and Neurodevelopment.Current environmental health reports · 2014Article
- Proposed mechanistic description of dose-dependent BDE-47 urinary elimination in mice using a physiologically based pharmacokinetic model.Toxicology and applied pharmacology · 2013Article
- The use of biomonitoring data in exposure and human health risk assessment: benzene case study.Critical reviews in toxicology · 2013Review
- The PBDE-209 exposure during pregnancy and lactation impairs immune function in rats.Mediators of inflammation · 2012Article
- Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities.Toxicologic pathology · 2012Article
- Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice.Toxicology and applied pharmacology · 2011Article
- Leveraging Epidemiology to Improve Risk Assessment.The open epidemiology journal · 2011Article
- Longitudinal biomonitoring for polybrominated diphenyl ethers (PBDEs) in residents of the Great Lakes basin.Chemosphere · 2010Article
- Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters.Toxicological sciences : an official journal of the Society of Toxicology · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of biomonitoring data holds promise for characterizing exposure and informing risk assessment. Biomonitoring data have been used successfully to track population trends, identify susceptible populations, and provide indications of emerging environmental health issues. However, there remain challenges associated with interpreting biomonitoring data for risk assessment. An international biomonitoring workshop was convened in September 2004 to explore the use of biomonitoring data in the context of risk assessment. Six compounds were examined as case studies for this workshop, including polybrominated diphenyl ethers (PBDEs). The PBDE case study was developed to provide an example of a persistent compound for which relatively few data are available for human exposure, biomonitoring, and health outcomes. PBDEs are used in hard plastics, electronics, textiles, and polyurethane foam products. The congener pattern downstream of production facilities often resembles the commercial mixture. However, because these compounds persist in the environment and in biota, the patterns of congeners evolve. PBDEs partition into body lipids, and direct measurement of bromodiphenyl ether congeners in biologic specimens provides a good marker of exposure. Data indicate significant variability (> 100-fold range) in lipid-adjusted levels for PBDEs in the general population. It is hypothesized that both exposure and pharmacokinetics may play a role in observed congener profiles. Significant gaps in our ability to interpret PBDE biomonitoring data to address public health and risk assessment questions include limited knowledge of environmental fate and transport of PBDE congeners, limited population-based data for adults, and lack of data for potentially vulnerable populations such as children.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.