Evidence map›Paper›PMID 17103417›Full record

Trial reportThe International journal of eating disorders2007

Placebo response in binge eating disorder.

M Joy Jacobs-Pilipski, Denise E Wilfley, Scott J Crow, B Timothy Walsh, Lisa R R Lilenfeld, Delia Smith West, Robert I Berkowitz, James I Hudson, Christopher G Fairburn

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Expectation shapes hunger and craving: placebo effects of verbal suggestion on food-related experiences.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2026
    Trial
  2. Trial
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  5. Article
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  12. Are loss of control while eating and overeating valid constructs? A critical review of the literature.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017
    Review
  13. Review
  14. Article
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  17. Diagnosis and management of binge eating disorder.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 2 countries.

M Joy Jacobs-PilipskiUCSD Eating Disorders Treatment Center, San Diego, California, USA.
Denise E Wilfley
Scott J Crow
B Timothy Walsh
Lisa R R Lilenfeld
Delia Smith West
Robert I Berkowitz
James I Hudson
Christopher G Fairburn
Children's Hospital of Philadelphia · USGeorgia State University · USHarvard University · USNewYork–Presbyterian Hospital · USUC San Diego Health System · USUniversity of Arkansas for Medical Sciences · USUniversity of Minnesota · USUniversity of Oxford · GBWashington University in St. Louis · US

Funding

Wellcome Trust 046386Wellcome Trust 079113
6 · The paper itself

Abstract

objectivePlacebo response in studies of binge eating disorder (BED) has raised concern about its diagnostic stability. The aims of this study were (1) to compare placebo responders (PRs) with nonresponders (NRs); (2) to investigate the course of BED following placebo response; and (3) to examine attributions regarding placebo response.

methodThe baseline placebo run-in phase (BL) was part of a RCT investigating sibutramine hydrochloride for BED; it included 451 participants, ages 19-63, diagnosed with BED. Follow-up (FU) included 33 PRs.

results: In this study, 32.6% of participants responded to placebo (PRs = 147; NRs = 304). PRs exhibited significantly less symptom severity. At FU (n = 33), many PRs reported continued symptoms.

conclusionPRs exhibited significantly less severe pathology than NRs. Placebo response in BED may transitory or incomplete. The results of this study suggest variable stability in the BED diagnosis.

Indexed as

Placebo EffectAdolescentAdultAgedAppetite DepressantsBulimia NervosaCyclobutanesFemaleHumansMaleMiddle AgedAppetite DepressantsCyclobutanessibutramine

Identifiers

PMID17103417
PMCPMC2798075
OpenAlexW1974310105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.