Evidence map›Paper›PMID 1710335›Full record

ArticlePflugers Archiv : European journal of physiology1991

Multiple types of Ca2+ channels in visceral smooth muscle cells.

M B Vivaudou, J J Singer, J V Walsh

Abstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Electrophysiology of Ctenophore Smooth Muscle.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  2. Article
  3. Article
  4. Near-membrane [Ca2+] transients resolved using the Ca2+ indicator FFP18.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Article
  5. Article
  6. ATP and G proteins affect the runup of the Ca2+ current in bovine chromaffin cells.Pflugers Archiv : European journal of physiology · 1995
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M B VivaudouDepartment of Physiology, University of Massachusetts Medical School, Worcester 01655.
J J Singer
J V Walsh
University of Massachusetts Chan Medical School · US

Funding

IONIC CHANNELS IN DISSOCIATED SMOOTH MUSCLE CELLSR01DK031620 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WALSH, JOHN V · 1986 to 2000
$412k
NIDDK NIH HHS DK31620
6 · The paper itself

Abstract

Single-channel currents were recorded from two classes of Ca2+ channels in visceral smooth muscle cells isolated from the stomach of the toad, Bufo marinus: a class of small-conductance channels (approximately 11 pS) and a class of large-conductance channels (approximately 26 pS). Small-conductance channels were present in a majority of patches and gave rise to a slowly inactivating current (t1/2 approximately 250 ms at 0 mV). Openings of large-conductance channels could be unequivocally resolved only in the presence of the dihydropyridine Ca2+ agonist Bay K 8644. Two subtypes of the large-conductance channels were found--those with a very slow rate of decay (greater than 500 ms) and those with a faster one (less than 100 ms). Large-conductance channels resemble L-type Ca2+ channels of other preparations. Small-conductance channels do not fit unambiguously into the other existing categories (i.e., N or T). Correspondence between single-channel and macroscopic Ca2+ currents is discussed.

Indexed as

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterAnimalsBariumBufo marinusCalcium ChannelsDihydropyridinesElectric ConductivityGastric MucosaIn Vitro TechniquesKineticsMuscle, SmoothStomach1,4-dihydropyridine3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterBariumCalcium ChannelsDihydropyridines

Identifiers

PMID1710335
OpenAlexW2011656096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.