Evidence map›Paper›PMID 17103317›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2006

Diagnostic accuracy of cardiac markers for myocardial damage after radiofrequency catheter ablation.

Hideo Hirose, Kimihiko Kato, Osamu Suzuki, Tetsuro Yoshida, Mitsutoshi Oguri, Kazuhiro Yajima, Takeshi Hibino, Kiyoshi Yokoi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Myocardial injury during radiofrequency and cryoablation of typical atrial flutter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2016
    Trial
  3. Article
  4. Article
  5. Remote magnetic versus manual catheters: evaluation of ablation effect in atrial fibrillation by myocardial marker levels.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hideo HiroseDepartment of Cardiovascular Medicine, Gifu Prefectural Government TAJIMI Hospital, Tajimi, Gifu 5078522, Japan.
Kimihiko Kato
Osamu Suzuki
Tetsuro Yoshida
Mitsutoshi Oguri
Kazuhiro Yajima
Takeshi Hibino
Kiyoshi Yokoi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study compares serum markers of myocardial damage incurred during radiofrequency catheter ablation (RFCA). METHODS AND

resultsBlood was sampled from 34 patients with atrial flutter (n = 16), atrioventricular nodal reentrant tachycardia (AVNRT; n = 13), and Wolff-Parkinson-White syndrome (WPW; n = 5) to measure creatine kinase MB subfraction (CK-MB), human heart-type fatty acid protein (h-FABP), and cardiac troponin T (cTnT) values at baseline and after RFCA. The controls comprised 12 patients without significant elevation of all myocardial markers during electrophysiological study (EPS) without RFCA. h-FABP values did not elevate significantly, whereas CK-MB and cTnT demonstrated significant change after RFCA (P < 0.001). Neither peak h-FABP nor CK-MB correlated with following RFCA parameters: delivery duration, number of RFCA discharges, and cumulative RFCA energy. In contrast, correlations were significant between mean peak values of cTnT and these RFCA parameters (all P < 0.05). The sensitivity (71.6%) and specificity (35.6%) of h-FABP were inferior to those of cTnT (93.3% and 89.8%, respectively).

conclusionh-FABP is an insensitive and less specific marker of myocardial damage in RFCA much along the lines of CK-MB and when compared with the proven accuracy of cTnT.

Indexed as

AdultAgedArrhythmias, CardiacAtrial FlutterBiomarkersCatheter AblationCreatine Kinase, MB FormElectrophysiologic Techniques, CardiacFatty Acid Binding Protein 3Fatty Acid-Binding ProteinsFemaleHumansMaleMiddle AgedMyocardiumROC CurveBiomarkersCreatine Kinase, MB FormFABP3 protein, humanFatty Acid Binding Protein 3Fatty Acid-Binding ProteinsTroponin T

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.