Evidence map›Paper›PMID 17102947›Full record

ArticleRheumatology international2007

A novel therapeutic option in Cogan diseases? TNF-alpha blockers.

M Fricker, A Baumann, F Wermelinger, P M Villiger, A Helbling

Open access · bronzeAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. COGAN'S SYNDROME.Romanian journal of ophthalmology
    Pooled it
  3. Article
  4. Article
  5. Pediatric uveitis: Role of the pediatrician.Frontiers in pediatrics · 2022
    Review
  6. Review
  7. Review
  8. Review
  9. Cogan's syndrome--clinical guidelines and novel therapeutic approaches.Clinical reviews in allergy & immunology · 2014
    Review
  10. Unique topics and issues in rheumatology and clinical immunology.Clinical reviews in allergy & immunology · 2014
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Otosclerosis: an organ-specific inflammatory disease with sensorineural hearing loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2009
    Article
  17. Cogan's syndrome: present and future directions.Rheumatology international · 2009
    Review
  18. Article
  19. The use of TNF-alpha blockers in Cogan's syndrome.Rheumatology international · 2007
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M FrickerDivision of Allergology, Policlinics of Allergy and Immunology, Department of Rheumatology and Clinical Immunology/Allergology, University Hospital (Inselspital), Bern, Switzerland.
A Baumann
F Wermelinger
P M Villiger
A Helbling
University Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cogan's syndrome is characterized by noninfectious, interstitial keratitis combined with a vestibulo-auditory deficit. Despite therapy with corticosteroids in combination with immunosuppressive agents, relapses occurred in two subjects and the clinical course suggested a progression of the disease. Treatment with anti-TNF-alpha was started leading to a rapid and sustained clinical remission for over 2 respectively 3 years.

Indexed as

AdultAntibodies, MonoclonalHearing Loss, BilateralHumansInfliximabMaleMiddle AgedOtitisRemission InductionRheumatic DiseasesSyndromeTumor Necrosis Factor-alphaAntibodies, MonoclonalInfliximabTumor Necrosis Factor-alpha

Identifiers

PMID17102947
OpenAlexW2046001645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.