ArticleLearning & memory (Cold Spring Harbor, N.Y.)
Effects of nucleus basalis magnocellularis stimulation on a socially transmitted food preference and c-Fos expression.
Article in Learning & memory (Cold Spring Harbor, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data.Scientific reports · 2021Pooled it
- Deep brain stimulation of the nucleus basalis of Meynert in neurodegenerative diseases with cognitive impairment: An update on evidence and mechanisms.Neural regeneration research · 2026Article
- Cannabidiol enhances socially transmitted food preference: a role of acetylcholine in the mouse basal forebrain.Psychopharmacology · 2025Article
- Patterns of Arc mRNA expression in the rat brain following dual recall of fear- and reward-based socially acquired information.Scientific reports · 2023Article
- Modulation of Human Memory by Deep Brain Stimulation of the Entorhinal-Hippocampal Circuitry.Neuron · 2020Review
- Deep brain stimulation: potential for neuroprotection.Annals of clinical and translational neurology · 2019Review
- Nucleus Basalis of Meynert Stimulation for Dementia: Theoretical and Technical Considerations.Frontiers in neuroscience · 2018Article
- Assessment of potential targets for deep brain stimulation in patients with Alzheimer's disease.Journal of clinical medicine research · 2015Review
- Disease-modifying therapeutic directions for Lewy-Body dementias.Frontiers in neuroscience · 2015Review
- Deep brain stimulation as a tool for improving cognitive functioning in Alzheimer's dementia: a systematic review.Frontiers in psychiatry · 2013Review
- The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Acetylcholine release in the hippocampus and prelimbic cortex during acquisition of a socially transmitted food preference.Neurobiology of learning and memory · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experiment 1 examined the effects of electrical stimulation of nucleus basalis magnocellularis (NBM) on a relational odor-association task--the social transmission of food preference (STFP). Rats were stimulated unilaterally in the NBM for 20 min (100 microA, 1 Hz) immediately before the social training. They were tested on their ability to remember preference for the trained food either immediately or following a 24-h delay. Stimulation of NBM improved retention regardless of delay, and additional behavioral measures (social interaction, motor activity, or exploration) did not account for such effects. Experiment 2 investigated brain regions activated after NBM electrical stimulation by examining the induction of c-Fos. This treatment led to bilateral increased c-Fos expression in prefrontal regions, such as orbitofrontal, prelimbic, and infralimbic cortices, and some hippocampal subregions (dorsal CA and ventral dentate gyrus). In contrast, no differences between groups in c-Fos expression were found in basolateral amygdala, dorsal dentate gyrus, ventral CA, or ventral subiculum. Present findings indicate that pretraining NBM electrical stimulation facilitates the acquisition of STFP, supporting a role of NBM in the early stages of memory formation, and suggest that the treatment might cause such effects by inducing neural changes, related to transcription factors such as c-Fos, in the prefrontal cortex or the hippocampal formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.