Evidence map›Paper›PMID 17101650›Full record

ArticleInfection and immunity2007

Identification of the gene encoding the FhbB protein of Treponema denticola, a highly unique factor H-like protein 1 binding protein.

John V McDowell, Jesse Frederick, Lola Stamm, Richard T Marconi

Abstract read
In one paragraph

Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. International journal of environmental research and public health · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Treponema denticola interactions with host proteins.Journal of oral microbiology · 2012
    Article
  15. Review
  16. Crystallization of the factor H-binding protein, FhbB, from the periopathogen Treponema denticola.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John V McDowellDepartment of Microbiology and Immunology, Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia 23298-0678, USA.
Jesse Frederick
Lola Stamm
Richard T Marconi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gene encoding the Treponema denticola factor H-like protein 1 (FHL-1) binding protein, FhbB, was recovered and characterized. Sequence conservation, expression, and properties of FhbB were analyzed. The identification of FhbB represents an important step in understanding the contribution of FHL-1 binding in T. denticola pathogenesis and in development of periodontal disease.

Indexed as

Bacterial ProteinsComplement C3b Inactivator ProteinsComplement Factor HConserved SequenceDNA, BacterialGene ExpressionMolecular Sequence DataProtein BindingReverse Transcriptase Polymerase Chain ReactionRNA, BacterialRNA, MessengerSequence Analysis, DNASequence Homology, Amino AcidTreponema denticolaVirulence FactorsBacterial ProteinsCFHR1 protein, humanComplement C3b Inactivator ProteinsComplement Factor HDNA, BacterialRNA, BacterialRNA, MessengerVirulence Factors

Identifiers

PMID17101650
PMCPMC1828522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.